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Table 2 Mean days to negative sputum smears among the subgroups

From: Fixed-dose combination associated with faster time to smear conversion compared to separate tablets of anti-tuberculosis drugs in patients with poorly controlled diabetes and pulmonary tuberculosis in Qatar

 

FDC mean days±SD (n)

ST mean days±SD (n)

p-value

AFB load

 1+

25.9 ± 14.8 (10)

20.8 ± 4.6 (4)

NS

 2+

34.3 ± 20.5 (19)

38.4 ± 33.6 (16)

NS

 3+

36.6 ± 19.5 (21)

56.1 ± 28.8 (27)

0.008

Weight bands

 35–54 kg

37.2 ± 22

43 ± 22.5

NS

  > 54 kg

31.8 ± 16.4

45.7 ± 33.2

NS

No metformin

25.7±16.4 (16)

45.6±5.1 (15)

0.012

Metformin (any dose)

34.9 ± 19.7 (38)

45.6 ± 34.8 (34)

NS

Metformin≥2000 mg/day

30.7 ± 13.4 (18)

62 ± 35.5 (11)

0.016

Metformin & AFB load 3+

41.1 ± 20.6 (15)

63.5 ± 32.4 (14)

0.038

Metformin≥2000 mg/day & AFB load 3+

36 ± 12.1 (6)

92.2 ± 26 (5)

0.001

  1. AFB acid-fast bacilli, FDC fixed-dose combination, NS not significant, ST separate tablets