Table 1 Baseline characteristics of the patients
|  | FDC (n = 54) | ST (n = 49) | p-value |
|---|---|---|---|
Age, mean ± SD | 45 ± 8.7 | 46.2 ± 9.5 | NS |
Asian ethnicity, n (%)a | 51 (94.4) | 40 (81.6) | NS |
Male gender, n (%) | 52 (96.3) | 41 (83.7) | NS |
Weight (kg), mean ± SDb | 59.2 ± 9.8 | 61.7 ± 12.3 | NS |
Weight bands, nb | |||
  < 35 kg | 0 | 0 | − |
 35–54 kg | 13 | 9 | NS |
  > 54 kg | 25 | 25 | NS |
Height (cm), mean ± SDc | 165.2 ± 7.8 | 164.1 ± 8 | NS |
Smokers, n (%) | 19 (35.2) | 13 (26.5) | NS |
Hypertension, n (%) | 11 (20.4) | 15 (30.6) | NS |
Vitamin D level, mean ± SDd | 19.5 ± 22.5 | 19.2 ± 8.5 | NS |
HbA1c, mean ± SD | 10.6 ± 2.5 | 10.8 ± 2.1 | NS |
AFB load, n (%) | |||
 1+ | 10 (18.5) | 4 (8.2) | NS |
 2+ | 19 (35.2) | 16 (32.7) | NS |
 3+ | 21 (38.9) | 27 (55.1) | NS |
Anti-TB dose (mg/kg), mean ± SD | |||
 Isoniazid | 4.8 ± 0.5 | 5 ± 0.9 | NS |
 Rifampin | 9.6 ± 1.1 | 9.6 ± 1.4 | NS |
 Pyrazinamide | 25.6 ± 2.6 | 24 ± 2.8 | 0.011 |
 Ethambutol | 17.5 ± 2 | 18.1 ± 4.1 | NS |
Patients received metformin, n (%) | 38 (70.4) | 34 (69.4) | NS |