Table 2 C-reactive protein and procalcitonin distributions by infection in 210 participants with a single target infection
Biomarker concentration | Total (N = 210) | TB (n = 133) | CAP (n = 61) | PJP (n = 16) | P-value c |
|---|---|---|---|---|---|
Median CRP mg/L (IQR) | 148 (96–224) | 141 (97–203) | 193 (108–264) | 106.5 (79.5–131.5) | TB vs.CAP: 0.02, CAP vs. PJP: 0.003 |
PJP vs. TB: 0.02 | |||||
CRP ≥ 10 mg/La n (%) | 206 (98) | 131 (98.5) | 60 (98.4) | 15 (93.8) | TB vs.CAP: 1.00d, CAP vs. PJP: 0.38d |
PJP vs. TB: 0.29d | |||||
Median PCT μg/L (IQR) | 0.8 (0.3–2.9) | 0.7 (0.4–2.1) | 2.0 (0.4–5.2) | 0.2 (0.1–1.3) | TB vs. CAP: 0.05, CAP vs. PJP: 0.01 |
PJP vs. TB: 0.05 | |||||
PCT ≥ 0.02 μg/Lb: n (%) | 209 (99.5) | 132 (99) | 61 (100) | 16 (100) | – |
PCT ≥ 0.1 μg/L: n (%) | 199 (94.8) | 128 (96.2) | 58 (95.1) | 13 (81.3) | TB vs. CAP: 0.71d,, CAP vs. PJP: 0.10d |
PJP vs. TB: 0.04d | |||||
PCT ≥ 0.25 μg/L: n (%) | 170 (81) | 112 (84) | 50 (82) | 8 (50) | TB vs. CAP: 0.70, CAP vs. PJP: 0.008 |
PJP vs: TB: 0.001 | |||||
PCT ≥ 0.5 μg/L: n (%) | 137 (65.2) | 87 (65.4) | 43 (70.5) | 7 (43.8) | TB vs. CAP: 0.49, CAP vs. PJP: 0.05 |
PJP vs. TB: 0.11 | |||||
PCT ≥ 2 μg/L: n (%) | 69 (32.9) | 36 (27.1) | 30 (49.2) | 3 (18.8) | TB vs. CAP: 0.003, CAP vs. PJP: 0.05d |
PJP vs. TB: 0.56d | |||||
PCT > 10 μg/L: n (%) | 16 (8) | 8 (6) | 8 (13) | 0 (0) | – |