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Table 4 Clinical outcomes in Infectious disease Intervention subgroup

From: Impact of matrix-assisted laser desorption/ionization time of flight mass spectrometric evaluation on the clinical outcomes of patients with bacteremia and fungemia in clinical settings lacking an antimicrobial stewardship program: a pre-post quasi experimental study

Outcomes

Conventional period

n = 79 (%)

MALDI-TOF period

n = 75 (%)

P Value†

Time to pathogen identification (hours)

86.9 ± 30.4

62.5 ± 23.1

< 0.001

Time to effective therapy (hours)

27.8 ± 32.4

17.1 ± 25.7

0.031

30-day all-cause mortality

7 (8.9)

5 (6.7)

0.612

Time to microbiological clearance (days)

4.1 ± 3.0

3.4 ± 2.0

0.081

Length of ICU stay (days)

14.1 ± 26.0

11.7 ± 12.8

0.719

30-day Recurrence of same BSI

2 (2.5)

0 (0.0)

0.497

  1. *Abbreviations: MALDI-TOF matrix-assisted laser desorption/ionization time-of-flight, ICU intensive care unit, BSI bloodstream infection
  2. P-values were calculated using the chi-square or Fisher’s exact test for categorical variables and Student’s t-test for continuous variables