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Table 1 Susceptibility to the antimicrobial agents, basic characterization and drug resistance gene of CNSE

From: Molecular characterization and epidemiology of carbapenem non-susceptible Enterobacteriaceae isolated from the Eastern region of Heilongjiang Province, China

Isolate NO. MIC(ug/mL) bla genotype MHT/mCIM strain Culture type History of antibiotic use Invasive procedure outcome MLST
AMP AMS TZP CZO CAZ CRO FEP ATM IMP AMK GEN TOB CIP LEV
CNSE01
CNSE02
CNSE15
R R R R R R R R R S R R R S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES Survived ST76
CNSE03
CNSE09
CNSE12
CNSE44
CNSE48
R R R R R R R R R S R R I S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES Died ST76
CNSE04
CNSE05
CNSE07
CNSE14
CNSE16
CNSE29
CNSE30
CNSE31
CNSE32
CNSE34
CNSE35
CNSE54
R R R R R R R R R S R R I S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES Survived ST76
CNSE06 R R R R R R R R R S S S S S KPC-2, SHV +/+ KP Sputum YES YES Died ST323
CNSE08
CNSE11
R R R R R R R R R S R R R R KPC-2, SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES Survived ST76
CNSE10 R R R R R R R R R S R R I S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Sputum NO NO Survived ST76
CNSE17 R R R R R R R R R S R R S S KPC-2, SHV, CTX-M-15 +/− KP Sputum YES YES Died ST76
CNSE18 R R R R R R R R R S R R I S KPC-2, SHV, CTX-M-15 +/+ KP Sputum YES YES Died ST76
CNSE19 R R R R R R R R R S S I R R KPC-2, NDM-5, CTX-M-14, TEM −/+ EC Blood YES YES Survived ND
CNSE20 R R R R R R R R R S R R I S KPC-2, NDM-5, SHV, CTX-M-177, TEM +/+ KP Sputum YES YES Died ST76
CNSE22 R R R R R R R R R S R I S S IMP-4, SHV, TEM +/+ KP Sputum YES YES Died ST896
CNSE23 R R R R R R R R R S R R R R KPC-2, SHV, TEM, CTX-M-15 +/+ KP Blood YES YES NR ST76
CNSE24 R R R R R R R R R S R R I S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Blood YES YES Survived ST76
CNSE25 R R R R R R R R R S R R R R NDM-1, TEM, CTX-M-15 +/+ EC Sputum YES YES Survived ND
CNSE26 R R R R R R R S R S S S S S IMP-4 +/+ KO Sputum YES NO Survived ND
CNSE27 R R R R R R R R R R R R R R NDM-7, TEM, CTX-M-15 −/+ EC Urine YES YES Survived ND
CNSE28 R R R R R R R R R S R R I S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Blood YES YES Died ST76
CNSE36 R R R R R R R R R S R R R I KPC-2, SHV, TEM, CTX-M-15 +/+ KP Secretion YES YES Survived ST76
CNSE37 R R R R R R R R I S R I S S IMP-4, SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES Died ST2964
CNSE38 R R R R R R R R R S R R S S NDM-1, SHV, CTX-M-15 −/+ ECL Secretion YES YES Survived ND
CNSE39 R R R R R R R R R S S S S S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES Survived ST76
CNSE40 R R R R R R R R R S R R I S KPC-2, SHV, TEM, CTX-M-15 +/+ KO Sputum YES YES Survived ND
CNSE41 R R R R R R R R S S R R R S −/+ SM Secretion NR NR NR ND
CNSE42 R R R R R R R R I R R R S S IMP-4, TEM +/+ ECL Blood YES YES Died ND
CNSE43 R R R R R R R R R S R R R R KPC-2, SHV, TEM, DHA +/+ ECL Sputum YES YES Died ND
CNSE45 R R R R R R R R R R R R R R KPC-2, TEM +/+ CF pus YES YES Survived ND
CNSE46 R R R R R R R R R S R I R R NDM-1
IMP-4, SHV, TEM, CTX-M-15
+/+ ECL Urine YES YES Survived ND
CNSE47 R R R R R R R R R S S S R R KPC-2, SHV −/+ KP Blood YES YES Survived ST11
CNSE49 R R R R R R R R R S R R R S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Blood YES YES Survived ST76
CNSE50 R R R R R R R R R S R R R R KPC-2, TEM, CTX-M-15 +/+ KP Sputum YES YES Survived ST76
CNSE51 R R R R R R R R R S S S R R KPC-2, IMP-4, TEM, DHA +/+ ECL pus YES YES Survived ND
CNSE52 R R R R R R R R R S R R I S KPC-2, TEM, CTX-M-15 +/+ KP Sputum YES YES Survived ST76
CNSE53 R R R R R R R S R R R R R R NDM-5, SHV +/+ EC Blood YES YES Died ND
CNSE55 R R R R R R R R R S R R R S KPC-2, SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES NR ST76
CNSE56 R R R R R R R R R S R R R S SHV, TEM, CTX-M-15 +/+ KP Sputum YES YES Survived ST76
  1. AMP ampicillin, AMS ampicillin-sulbactam, TZP piperacillin/tazobactam, CZO cefazolin, CAZ ceftazidime, CRO ceftriaxone, FEP cefepime, ATM aztreonam, IMP imipenem, GEN gentamicin, TOB tobramycin, AMK amikacin, CIP ciprofloxacin and LEV levofloxacin, KP Klebsiella pneumoniae, EC Enterobacter cloacae, EC Escherichia coli, KO Klebsiella oxytoca, CF Citrobacter freundii, SM Serratia marcescens, NR No Record, ND Not Determined