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Table 4 Risk factors for lipoatrophy in HIV-infected children in the Maggsen cohort study.a–b Dakar, Senegal

From: Low prevalence of lipodystrophy in HIV-infected Senegalese children on long-term antiretroviral treatment: the ANRS 12279 MAGGSEN Pediatric Cohort Study

Characteristics Univariable analysisc Multivariable analysisd
OR 95% CI P value aOR 95% CI P value
Boys vs. girls 4.3 1.6–11.6 0.004 4.3 1.6–11.7 0.005
Stavudine exposure
  ≥ 1 year vs. no 3.6 1.0–12.6 0.04 3.8 1.0–14.0 0.04
  < 1 year vs. no 1.5 0.5–4.8 0.48 1.4 0.4–4.4 0.59
Lopinavir/r exposure
  ≥ 3 years vs. no 2.2 0.9–5.4 0.09
  < 3 years vs. no 0.3 0.0–2.5 0.28
 Moderate wastinge: yes vs.no 1.7 0.7–3.9 0.20
 Age ≥ 10 vs. <  10 years 1.3 0.6–2.9 0.54
  1. aAbbreviations: aOR adjusted odds ratio, CI confidence interval, Lopinavir/r lopinavir/ritonavir, OR odds ratio
  2. bNo missing for multivariable model
  3. cExplanatory variables are included at P < 0.25 in multivariate analysis
  4. dExplanatory variables are exited at P ≥ 0.20
  5. eModerate wasting (moderate acute malnutrition) is defined for both weight-for-height z scores (WHZ) in children < 5 years or body mass index-for-age z score (BMIZ) in children ≥5 years as being ≥ − 3 and < − 2 [20, 21]