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Table 4 Risk factors for lipoatrophy in HIV-infected children in the Maggsen cohort study.a–b Dakar, Senegal

From: Low prevalence of lipodystrophy in HIV-infected Senegalese children on long-term antiretroviral treatment: the ANRS 12279 MAGGSEN Pediatric Cohort Study

Characteristics

Univariable analysisc

Multivariable analysisd

OR

95% CI

P value

aOR

95% CI

P value

Boys vs. girls

4.3

1.6–11.6

0.004

4.3

1.6–11.7

0.005

Stavudine exposure

  ≥ 1 year vs. no

3.6

1.0–12.6

0.04

3.8

1.0–14.0

0.04

  < 1 year vs. no

1.5

0.5–4.8

0.48

1.4

0.4–4.4

0.59

Lopinavir/r exposure

  ≥ 3 years vs. no

2.2

0.9–5.4

0.09

–

–

–

  < 3 years vs. no

0.3

0.0–2.5

0.28

–

–

–

 Moderate wastinge: yes vs.no

1.7

0.7–3.9

0.20

–

–

–

 Age ≥ 10 vs. <  10 years

1.3

0.6–2.9

0.54

–

–

–

  1. aAbbreviations: aOR adjusted odds ratio, CI confidence interval, Lopinavir/r lopinavir/ritonavir, OR odds ratio
  2. bNo missing for multivariable model
  3. cExplanatory variables are included at P < 0.25 in multivariate analysis
  4. dExplanatory variables are exited at P ≥ 0.20
  5. eModerate wasting (moderate acute malnutrition) is defined for both weight-for-height z scores (WHZ) in children < 5 years or body mass index-for-age z score (BMIZ) in children ≥5 years as being ≥ − 3 and < − 2 [20, 21]
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BMC Infectious Diseases

ISSN: 1471-2334

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