Table 1 Baseline characteristics of patients according to ARV regimen
Baseline characteristics | Non TDF n = 145 | Non-boosted TDF n = 78 | TDF + Boosted PI n = 50 | p |
|---|---|---|---|---|
Male, n, (%) | 127 (87.6) | 67 (85.9) | 45 (90.0) | 0.78 |
Mean age ± SD (years) | 47 ± 6 | 47 ± 6 | 45 ± 6 | 0.79 |
Baseline mean creatinine ± SD (mg/dL) | 0.84 ± 0.19 | 0.8 ± 0.13 | 0.9 ± 0.14 | 0.05 |
Baseline mean eGFR ± SD (ml/min/1.73m2) | 100.9 ± 16.3 | 104.1 ± 11.3 | 98.2 ± 11.8 | 0.06 |
Body mass index ± SD (Kg/m2) | 23.3 ± 3.9 | 22.3 ± 4.3 | 22.8 ± 3.8 | 0.24 |
Diabetes, n (%) | 5 (3.4) | 4 (5.1) | 1 (2.0) | 0.63 |
Hypertension, n (%) | 21 (14.5) | 10 (12.8) | 4 (8.0) | 0.47 |
Median CD4+ cell count ± IQ (/mm3) | 618 (457–868) | 611 (443–762) | 506 (279–807) | 0.12 |
VL HIV < 20 cp/mL, n (%) | 138 (95.2) | 76 (97.4) | 44 (88) | 0.09 |
Median stiffness ± IQ (kPa) | 9.4 (6.4–15.4) | 9.5 (6.9–12.3) | 10.5 (7.4–18.2) | 0.74 |
Cirrhosis, n (%) | 53 (36.6) | 19 (24.4) | 22 (44.0) | 0.051 |
Median MELD ± IQ | 7 (6–8) | 7 (6–7) | 7 (7–9) | 0.07 |
Child-Pugh A, n (%) | 33 (62.2) | 8 (42.1) | 9 (40.9) | 0.10 |
SOF/LDV 24 weeks, n (%) | 42 (27.2) | 24 (30.0) | 19 (38.0) | 0.50 |
Ribavirin use, n (%) | 28 (18.4) | 14 (17.5) | 9 (18.0) | 0.96 |