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Table 4 Prevalence of torque teno viruses stratified by gender in the study group

From: Prevalence of human anelloviruses in Romanian healthy subjects and patients with common pathologies

Group Viral DNA positivity rate
TTV TTDMV TTMV
T1DM 73.3%** 62.7%* OR = 1.9 (95% CI 1.3–2.7) 53.4%* OR = 2.4 (95% CI 1.7–3.4)
 Men 74.7%** (65/87) 62.1%** (54/87) 46%** (40/87)
 Women 71.6%** (53/74) 63.5%** (47/74) 62.1% (46/74)* OR = 3.309 (95% CI 2–5.5)
T2DM 75%* OR = 2.1 (95% CI 1.7–2.7) 61.8%* OR = 1.8 (95% CI 1.5–2.3) 50.3%* OR = 2.1 (95% CI 1.7–2.7)
 Men 78.1%* OR = 2.4 (95% CI 1.6–3.4) 58.9%** 50%* OR = 2.3 (95% CI 1.6–3.2)
 Women 71.8%* OR = 1.9 (95% CI 1.3–2.6) 64.9%* OR = 2 (95% CI 1. 5–2.7) 50.6%* OR = 2.1 (95% CI 1.5–2.8)
Obesity 70.4% 47.2% 31.2%
 Men 68% (44/65) 33.8% (22/65) 26.1% (17/65)
 Women 73.3% (44/60) 61.6% (37/60) 36.6% (22/60)
Hypertension 74.2%* OR = 2 (95% CI 1.6–2.6) 59.6%* OR = 1.7 (95% CI 1.3–2.1) 46.4%* OR = 1.8 (95% CI 1.4–2.3)
 Men 74.8%* OR = 2 (95% CI 1.4–2.8) 57.7%** 45.6%* OR = 1.9 (95% CI 1.3–2.7)
 Women 73.6%* OR = 2 (95% CI 1.5–2.8) 61.5%** 47.2%* OR = 1.8 (95% CI 1.3–2.4)
Chronic Periodontitis 74.1%** 58.8%** 42.1%
 Men 75.8% 56.3% 43.8%
 Women 73.1%** 60.4% 41.1%
breast cancer 80.6%* OR = 3 (95% CI 1.7–5) 72.8%* OR = 2.9 (95% CI 1.9–4.9) 37.8%
overall patients 73.4%* OR = 1.9 (95% CI 1.6–2.3) 58.7%* OR = 1.6 (95% CI 1.3–1.9) 44.3%* OR = 1.7 (95% CI 1.4–2)
 Men 73.4%* OR = 1.8 (95% CI 1.3–2.5) 54.4%** 41.7%**
 Women 73.4%* OR = 2 (95% CI 1.6–2.6) 62.4%* OR = 1.8 (95% CI 1.4–2.3) 46.7%* OR = 1.7 (95% CI 1.4–2.3)
healthy subjects 58.5% 46.4% 32.1%
 Men 59.9% 44% 30.5%
 Women 57.5% 48% 33.2%
  1. T1DM – type 1 diabetes mellitus, T2DM – type 2 diabetes mellitus, OR – Odds Ratio, *Chi squared/Fisher exact p < Bonferroni corrected alpha = 0.0003 compared with healthy subjects; **Chi squared/Fisher exact p < 0.05