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Table 2 Association between the presence of anelloviral DNA and history of HAV infection or different medical procedures in the overall study group

From: Prevalence of human anelloviruses in Romanian healthy subjects and patients with common pathologies

Variable History of HAV infection (n = 390) Surgical proceduresa (n = 777) Undergone dialysis/transfusions (n = 190)
TTV DNA positive 304 (77.9%)*
OR = 1.8 (95% CI 1.4–2.4)
591 (76%)*
OR = 1.8 (95% CI 1.5–2.3)
169 (88.9%)*
OR = 4.1 (95% CI 2.6–6.6)
Men Women Men Women Men Women
152/189 (80.4%)*
OR = 2.1 (95% CI 1.4–3.1)
152/201 (75.6%)** 112/130 (86.1%)*
OR = 3.2 (95% CI 1.9–5.3)
475/647 (73.4%)*
OR = 2 (95% CI 1.6–2.6)
69/79 (87.3%)*
OR = 3.3 (95% CI 1.7–6.6)
100/111 (90.1%)*
OR = 4.9 (95% CI 2.6–9.3)
TTMDV DNA positive 260 (66.7%)*
OR = 1.9 (95% CI 1.5–2.4)
507 (65.2%)*
OR = 2 (95% CI 1.7–2.5)
149 (78.4%)*
OR = 3.4 (95% CI 2.3–4.8)
Men Women Men Women Men Women
128/189 (67.7%)*
OR = 2.4 (95% CI 1.7–3.3)
132/201 (65.6%) ** 92/130 (70.7%)*
OR = 2.6 (95% CI 1.7–4)
414/647 (64%)*
OR = 2 (95% CI 1.5–2.5)
61/79 (77.2%)*
OR = 3.6 (95% CI 2.1–6.2)
88/111 (79.2%)*
OR = 3.2 (95% CI 2–5.1)
TTMV DNA positive 220 (56.4%)*
OR = 2.3 (95% CI 1.8–2.8)
383 (47.8%)*
OR = 1.8 (95% CI 1.5–2.2)
130 (68.4%)*
OR = 3.6 (95% CI 2.6–5)
Men Women Men Women Men Women
117 / 189 (61.9%)*
OR = 3.5 (95% CI 2.5–4.8)
103/201 (51.2%)** 83/130 (63.8%)*
OR = 3.5 (95% CI 2.3–5.1)
300/647 (46.3%)*
OR = 1.6 (95% CI 1.2–2)
61/79 (77.2%)*
OR = 6.8 (95% CI 3.7–11.1)
69/111 (62.1%)*
OR = 2.5 (95% CI 1.7–3.8)
  1. HAV – hepatitis A virus, OR = Odds Ratio, aat least one surgical procedure including breast cancer surgery, tonsillectomy, appendectomy, caesarean section, surgical abortion, septoplasty or aesthetic surgery; Statistical significance: *Chi Squared/Fisher exact p < Bonferroni corrected alpha = 0.0003 (compared with subjects without the analysed variable); **Chi Squared/Fisher exact p <  0.05