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Table 1 Subjects’ clinical and paraclinical characteristics

From: Prevalence of human anelloviruses in Romanian healthy subjects and patients with common pathologies

Variable

Healthy (n = 701)

Patients (n = 1299)

Statistical significance of differences (p-value)

Average age (years) ± SD

37.5 ± 11

49.1 ± 12.5

<  0.001a

Male/female gender

282/419 (40.2%/59.8%)

612/687 (47.1%/52.9%)

0.003b

Smokinge

190 (27.1%)

413 (31.8%)

<  0.001c

Drinkinge

128 (18.3%)

192 (14.8%)

0.95c

Physical activitye

501 (71.5%)

664 (51.1%)

<  0.001c

Orthopaedic trauma

 closed bone fractures

103 (14.7%)

328 (25.3%)

NA

 open bone fractures

0 (0%)

29 (2.2%)

NA

BMI

23.3 ± 1.8

39.9 ± 3.3

<  0.001a

Obesity

0 (0%)

125 (9.6%)

NA

Chronic periodontitis

0 (0%)

413 (31.8%)

NA

T1DM

0 (0%)

161 (12.4%)

NA

T2DM

 overall T2DM patients

0 (0%)

590 (45.4%)

NA

 of which undergone hemodyalisis

0 (0%)

150 (25.4%)

NA

Haemodialysis/transfusions

6 (0.9%)

184 (4.2%)

<  0.001d

Breast cancer

0 (0%)

103 (7.9%)

NA

History of hepatitis A virus infection

108 (15.4%)

282 (21.7%)

0.001b

TTV

410 (58.5%)

953 (73.4%)

<  0.001b

TTMDV

325 (46.4%)

762 (58.7%)

<  0.001b

TTMV

225 (32.1%)

576 (44.3%)

<  0.001b

  1. T1DM – type 1 diabetes mellitus, T2DM – type 2 diabetes mellitus, NA – not applicable esmokers, drinkers and occasional smokers and drinkers; occasional and regular physical activity (as reported by subjects); statistical tests: aindependent samples T test; bChi squared test; cKruskal-Wallis test; dFisher’s exact test