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Table 1 Subjects’ clinical and paraclinical characteristics

From: Prevalence of human anelloviruses in Romanian healthy subjects and patients with common pathologies

Variable Healthy (n = 701) Patients (n = 1299) Statistical significance of differences (p-value)
Average age (years) ± SD 37.5 ± 11 49.1 ± 12.5 <  0.001a
Male/female gender 282/419 (40.2%/59.8%) 612/687 (47.1%/52.9%) 0.003b
Smokinge 190 (27.1%) 413 (31.8%) <  0.001c
Drinkinge 128 (18.3%) 192 (14.8%) 0.95c
Physical activitye 501 (71.5%) 664 (51.1%) <  0.001c
Orthopaedic trauma
 closed bone fractures 103 (14.7%) 328 (25.3%) NA
 open bone fractures 0 (0%) 29 (2.2%) NA
BMI 23.3 ± 1.8 39.9 ± 3.3 <  0.001a
Obesity 0 (0%) 125 (9.6%) NA
Chronic periodontitis 0 (0%) 413 (31.8%) NA
T1DM 0 (0%) 161 (12.4%) NA
T2DM
 overall T2DM patients 0 (0%) 590 (45.4%) NA
 of which undergone hemodyalisis 0 (0%) 150 (25.4%) NA
Haemodialysis/transfusions 6 (0.9%) 184 (4.2%) <  0.001d
Breast cancer 0 (0%) 103 (7.9%) NA
History of hepatitis A virus infection 108 (15.4%) 282 (21.7%) 0.001b
TTV 410 (58.5%) 953 (73.4%) <  0.001b
TTMDV 325 (46.4%) 762 (58.7%) <  0.001b
TTMV 225 (32.1%) 576 (44.3%) <  0.001b
  1. T1DM – type 1 diabetes mellitus, T2DM – type 2 diabetes mellitus, NA – not applicable esmokers, drinkers and occasional smokers and drinkers; occasional and regular physical activity (as reported by subjects); statistical tests: aindependent samples T test; bChi squared test; cKruskal-Wallis test; dFisher’s exact test