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Table 1 Demographics of the study groups and biochemical parameters in TB-DM TB and HC

From: Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment

Study Demographics TB-DM TB HC p Value
No. of subjects recruited 64 24 24 –No significance
Gender (Male / Female) 44/20 17/7 14/10 –No significance
Median Age (Range) 52 (31–70) 43 (30–67) 35(27–62) –No significance
Median Height, cm 159 (129–176) 164 (121–181) 162 (125–190) –No significance
Median Weight, kg 49 (31–64) 44 (30–90) 55 (45–90) –No significance
Body mass index kg/m2 19.3 (13.2–32.6) 17.2 (12.2–21.2) 22.3 (18.2–24.7) –No significance
Smear Grade: 0/1+/2+/3+ 0/22/24/18 0/9/9/6 NA –No significance
Fasting Blood Glucose, mg/dL 158 (109–427) 93 (73–103) 88 (75–105) p < 0.0001
Post Prandial Glucose, mg/dL 220 (183–448) 112 (80–129) 110 (78–120) p < 0.0001
Glycated hemoglobin level, % 10.3 (7.3–15.6) 5.6 (5.0–5.8) 5.5 (5.0–5.7) p < 0.0001
  1. The values represent the geometric mean (and the 95% confidence intervals) except for age where the median (and the range) are depicted. P values were calculated using the Kruskal-Wallis test with Dunn’s post-hoc for multiple comparisons
  2. P values captured in bold are statistically significant