Fig. 2
From: Pulmonary blastomycosis presenting as primary lung cancer
Photomicrographs from the left upper lobe mass following resection. a Non-necrotizing granulomatous inflammation with visible intracellular yeast. b High-magnification demonstrates thick, double contoured yeast cell wall with internal nuclear detail (arrow). c Grocott’s methenamine silver (GMS) stain highlights yeast up to 10 μm in which budding is evident and appears both narrow-based (arrow) or relatively broad (far right). d-e Mucicarmine (d) and Fontana-Masson (e) stains fail to demonstrate capsular mucin and melanin production (arrows), respectively. A-B H&E 200× and 600×, respectively; c GMS, 600X; d mucicarmine, 600×; e Fontana-Masson, 600×