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Fig. 6 | BMC Infectious Diseases

Fig. 6

From: IL-17 and IL-22 production in HIV+ individuals with latent and active tuberculosis

Fig. 6

Mean values of IL-23R, ICOS and FoxP3 expression on CD4 + T cells after PD-1 neutralization. Freshly isolated PBMC (8 donors in each group) from HIV + LTBI+ individuals, and HIV + TB patients were cultured with or without ESAT6 and CFP10 (10 μg/ml each) and in the presence of anti-PD-1 or isotype control antibodies. After 96 h, the percentages CD4 + ICOS+ (a, b) CD4 + IL-23R+ (c, d), and CD4 + FoxP3+ (e, f) cells were determined by flow cytometry. Boxes show the median and interquartile range, and whiskers show the 5th and 95th percentile values

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