Fig. 5
From: IL-17 and IL-22 production in HIV+ individuals with latent and active tuberculosis
Mean cytokine values of cytokine levels after PD1 neutralization Freshly isolated PBMC (8 donors in each group) from HIV-LTBI+, HIV + LTBI+ individuals, and HIV + TB patients were cultured with or without ESAT6 and CFP10 (10 μg/ml each) and in the presence of anti-PD-1 or isotype control antibodies. After 96 h, cytokine levels in culture supernatants were determined by ELISA. Bars show (a, b) IL-17, (c, d) IL-22, (e, f) IFN-γ, (g, h) IL-10 levels in culture supernatants