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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: IL-17 and IL-22 production in HIV+ individuals with latent and active tuberculosis

Fig. 3

Mean values of CD4+ and CD8+ T-cell absolute counts and PD1 expression (a, b) Absolute CD4+ and CD8+ Tcells in blood. Whole blood from HIV-LTBI-, HIV-LTBI+, HIV + LTBI-, HIV + LTBI+ individuals, and HIV + TB+ patients (29 donors in each group) was collected. Four color staining (CD3, CD4, CD8 and CD45) was performed using TruCount tubes and data was analysed using MultiSET software. (c, d) PD-1 expression on CD4+ and CD8+ T-cells. Freshly isolated PBMC (21 donors in each group) from HIV-LTBI-, HIV-LTBI+, HIV + LTBI-, HIV + LTBI+ individuals, and HIV + TB+ patients were collected. The percentages of CD4 + PD-1+ and CD8 + PD-1+ cells were determined by flow cytometry. Data are shown as the median (horizontal line), 25th and 75th percentile values (box), and 5th and 95th percentile values (whiskers)

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