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Table 4 Rates of microbiological cure according to number of Grade 3 or 4 adverse events experienced by patients taking standard TB therapy

From: Toxicity associated with tuberculosis chemotherapy in the REMoxTB study

 

No. of grade 3/4 AEs

Microbiological cure

No microbiological cure

Total

Total

0

464 (90.8%)

47 (9.2%)

511

≥1

101 (78.9%)

27 (21.1%)

128

Related only

0

523 (89.9%)

59 (10.1%)

582

≥1

42 (73.7%)

15 (26.3%)

57

  1. Patients are grouped by the number of AEs they experienced in the trial. The number of patients who were either cured or not cured of their TB (based on definition given in Methods section) are displayed with row percentages (Chi square test p value < 0.001)