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Table 1 Clinical data of piglets with meningitis

From: The inflammatory response and neuronal injury in Streptococcus suis meningitis

animal no. lesiona intensity of the lesion semiquantitative bacterial loadb in CSF semiquantitative bacterial loadb in brain swabs age at time point of infection (in weeks) interval between infection and first signs of sickness (days)c interval between infection and termination of the experiment (days)
1 A mild +++ +++ 4 1 1.5
2 B; D severe +++ + 4 1.5 3
3 B; D severe +++ ++ 4 4 5.5
4 B severe +++ + 7 2.5 3.5
5 B severe +++ 9 1 2.5
6 A mild ++ ++ 9 1 3
7 B severe ++ + 9 6.5 7.5
8 C severe +++ +++ 9 2.5 3.5
9 B severe +++ + 9 6.5 7.5
10 B severe +++ 9 1 2.5
  1. aA = focal purulent meningitis
  2. B = diffuse purulent meningitis
  3. C = multi-focal purulent meningitis
  4. D = encephalitic involvement of the brain tissue
  5. bbacterial load: + < 50 colonies; ++ ≥50 colonies; +++ ≥500 colonies per plate; − no detection of the infection strain
  6. cfirst signs of sickness such as fever (≥ 40.2 °C), apathy, convulsions, lameness and anorexia