Table 1 Published cases of BCG spondylitis after BCG therapy (modified and supplemented from Obaid et al. [1] and Dąbrowska et al. [22])
Reference | Age | Time from BCG treatment to onset | Area of disease | Mycotic aortic aneurysm | Antituberculosis drugs used | Surgical intervention | Prognosis |
|---|---|---|---|---|---|---|---|
Katz [23] | 67 | 1.3 years | L4–5 | No | INH + RFP + EB | Yes | No long-term follow-up |
Fishman [24] | 90 | 1.3 years | T11–12 | No | INH + RFP + EB | Yes | Not specified |
Civen [25] | 81 | 7 months | T12-L1 | No | INH + RFP | Yes | Complete recovery |
Sugita [5] | 71 | 2 months | T7 | No | INH + RFP + SM | Yes | Not specified |
Morgan [26] | 77 | 0.5 months | T11-L1 | No | INH + RFP + EB | Yes | Functional after 1 year |
Rozenblit [9] | 76 | 5.7 years | L4 | Yes | INH + RFP + EB + CPFX | No | Asymptomatic at 8 months |
Aljada [27] | 79 | 2.5 years | L3 | No | INH + RFP | Yes | Leg weakness remaining after 1 year |
Abu-Nader [4] | 76 | 7 years | T6–7 | No | INH + RFP + EB | No | Symptoms improved |
Dahl [28] | 69 | 1 years | L3–4 | Yes | INH + RFP | Yes | Complete recovery |
Nikaido [29] | 86 | 1.8 years | T12-L1 | No | INH + RFP + EB | No | Complete recovery |
Mavrogenis [30] | 79 | 12 years | L3–4 | No | INH + RFP + EB | Yes | Pain-free at 18 months |
Patel [31] | 66 | 5 months | T10–11 | No | INH + RFP + EB | No | Symptoms improved at 3-month follow-up |
Colebatch [32] | 67 | 5 years | L4–5 | No | INH + RFP + EB | No | No long-term follow-up |
Josephson [15] | 75 | 6 months | L1–3 | No | INH + RFP | No | No long-term follow-up |
Obaid [1] | 67 | 11 months | L1–2 | No | INH + RFP + EB | Yes | Complete recovery |
Santbergen [10] | 58 | 3 years | T8–9 | Yes | INH + RFP | Yes | Complete recovery |
Samadian [7] | 94 | 5 months | L1–2 | Yes | Except PZA | No | No long-term follow-up |
Newman [2] | 80 | 3 years | T9–10 | No | INH + RFP + EB | Yes | Not specified |
Dąbrowska [22] | 67 | 1 month | T10–11 | No | INH + RFP + EB | Yes | Motor paralysis remaining |
Białecki [33] | 66 | 5 years | T11–12 | No | INH + RFP + PZA | Yes | Neurological disorders remaining |
Białecki [33] | 35 | 18 months | T5–6 | No | INH + RFP + PZA | No | Complete recovery |
Miyazaki [34] | 82 | 16 months | T5–6 | No | INH + RFP + EB | Yes | Complete recovery |