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Table 1 Published cases of BCG spondylitis after BCG therapy (modified and supplemented from Obaid et al. [1] and Dąbrowska et al. [22])

From: Bacille Calmette-Guérin (BCG) spondylitis with adjacent mycotic aortic aneurysm after intravesical BCG therapy: a case report and literature review

Reference Age Time from BCG treatment to onset Area of disease Mycotic aortic aneurysm Antituberculosis drugs used Surgical intervention Prognosis
Katz [23] 67 1.3 years L4–5 No INH + RFP + EB Yes No long-term follow-up
Fishman [24] 90 1.3 years T11–12 No INH + RFP + EB Yes Not specified
Civen [25] 81 7 months T12-L1 No INH + RFP Yes Complete recovery
Sugita [5] 71 2 months T7 No INH + RFP + SM Yes Not specified
Morgan [26] 77 0.5 months T11-L1 No INH + RFP + EB Yes Functional after 1 year
Rozenblit [9] 76 5.7 years L4 Yes INH + RFP + EB + CPFX No Asymptomatic at 8 months
Aljada [27] 79 2.5 years L3 No INH + RFP Yes Leg weakness remaining after 1 year
Abu-Nader [4] 76 7 years T6–7 No INH + RFP + EB No Symptoms improved
Dahl [28] 69 1 years L3–4 Yes INH + RFP Yes Complete recovery
Nikaido [29] 86 1.8 years T12-L1 No INH + RFP + EB No Complete recovery
Mavrogenis [30] 79 12 years L3–4 No INH + RFP + EB Yes Pain-free at 18 months
Patel [31] 66 5 months T10–11 No INH + RFP + EB No Symptoms improved at 3-month follow-up
Colebatch [32] 67 5 years L4–5 No INH + RFP + EB No No long-term follow-up
Josephson [15] 75 6 months L1–3 No INH + RFP No No long-term follow-up
Obaid [1] 67 11 months L1–2 No INH + RFP + EB Yes Complete recovery
Santbergen [10] 58 3 years T8–9 Yes INH + RFP Yes Complete recovery
Samadian [7] 94 5 months L1–2 Yes Except PZA No No long-term follow-up
Newman [2] 80 3 years T9–10 No INH + RFP + EB Yes Not specified
Dąbrowska [22] 67 1 month T10–11 No INH + RFP + EB Yes Motor paralysis remaining
Białecki [33] 66 5 years T11–12 No INH + RFP + PZA Yes Neurological disorders remaining
Białecki [33] 35 18 months T5–6 No INH + RFP + PZA No Complete recovery
Miyazaki [34] 82 16 months T5–6 No INH + RFP + EB Yes Complete recovery
  1. L lumbar vertebra, T thoracic vertebra, INH isoniazid, RFP rifampin, EB ethambutol, CPFX ciprofloxacin, PZA pyrazinamide