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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D3 as host directed therapy

Fig. 3

Generalized estimating equation (GEE) model was used to estimate the effect of adjunct therapy on LC3-expressing macrophages over time (week 0, 4, 8 and 12). β coefficient values are shown for three intervention groups (PBA, vitD3 and PBA + vitD3) compared to placebo. Arrowhead points represent the adjusted beta (β) coefficient values and vertical lines define 95% confidence intervals (CI). The analysis showed that mean % changes of LC3-expressing macrophage in PBA (β = 8.26; p < 0.001), vitD3 (β = 4.73; p = 0.037) and PBA+ vitD3 (β = 10.47; p < 0.001) were significantly higher compared to the placebo group

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