Table 1 Characteristics of studies included in the meta-analysis
Study | Year | Location | Research type | ICU type | NOS | Age, y (media) | Male/Femal | Period, month | Selected population | Sample | Detective way |
|---|---|---|---|---|---|---|---|---|---|---|---|
Domart [25] | 1990 | France | CP | S | 7 | 53 | 97/18 | 66 | Mediastinistis after cardiac surgery | Blood, urine | Culture |
Cook [24] | 1998 | USA | CR | S | 7 | NA | NA | 14 | Sepsis without bacteria or fungus | Blood, sputum | Culture |
Kutza [23] | 1998 | Germany | CP | S | 6 | 58 | 27/7 | NA | Sepsis | Blood | PCR, pp65 |
Heininger [22] | 2001 | Germany | CP | S | 7 | 68 | 35/21 | 12 | Seropositive patients after major surgery and trauma | Blood, sputum | PCR, Culture |
Cook [21] | 2003 | USA | CP | S | 8 | 59 | 62/42 | 15 | Sepsis, SICU stay>7d | Blood, sputum | Culture |
Jaber [20] | 2005 | France | CC | M-S | 6 | NA | 138/62 | 78 | fever>72Â h, without bacteria or fungus | Blood | pp65 |
von Muller [19] | 2006 | Germany | CP | M | 7 | NA | 15/10 | 9 | septic shock, ICU stay>7d | Blood | pp65 |
Limaye [18] | 2008 | USA | CP | M-S | 8 | 52 | 73/47 | 24 | Seropositive | Blood | PCR |
Ziemann [17] | 2008 | Germany | CR | S | 7 | NA | 33/66 | 33 | ICU stay>13d | Blood | PCR |
Chiche [16] | 2009 | France | CP | M | 7 | 63 | 159/83 | 24 | Mechanical ventilation16 | Blood, sputum | PP65, Culture |
Chilet [15] | 2010 | Spanish | CP | S | 7 | NA | 37/16 | 13 | Seropositive, ICU stay>5d | Blood, sputum | PCR |
Bordes [14] | 2011 | France | CP | S | 7 | 52 | 22/7 | 20 | Seropositive, burn patients, | Blood | PCR |
Heininger [13] | 2011 | Germany | CP | M-S | 7 | 68 | 67/19 | 30 | Seropositive, severe sepsis | Blood, sputum | PCR |
Osman [12] | 2014 | Egypt | CP | M | 7 | 59 | 29/22 | 3 | Mechanical ventilation | Blood | PCR |
Walton [11] | 2014 | France | CP | M-S | 7 | NA | 305/255 | 48 | Sepsis | Blood | PCR |
Ong [10] | 2015 | New Zealand | CP | M | 8 | NA | 196/110 | 24 | ARDS, Mechanical ventilation>4d | Blood | PCR |
Frantzeska [32] | 2015 | Greece | CP | M | 7 | 63 | 51/29 | 24 | Seropositive, mechanical ventilation | Blood | PCR |
Ong [33] | 2016 | Netherlands | CP | M | 7 | NA | 164/107 | 36 | ARDS, Mechanical ventilation>4d | Blood | PCR |