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Table 1 Index Case Demographic and Clinical Characteristics

From: Yield of household contact tracing for tuberculosis in rural South Africa

Variable

Overall (N = 130)

New TB in Householda (N = 9)

No New TB in Householdb (N = 121)

P-value*

N (%)

N (%)

N (%)

Female Sex

57 (44%)

3 (33%)

54 (45%)

0.731

Age (Median, IQR***)

40 (31–49)

36 (31–48)

39 (31–49)

0.831

Female-Headed Household

67 (52%)

7 (78%)

60 (50%)

0.166

Head of HH Income (Median, IQR)

1270 (13–2350)

2500 (1270–6300)

1270 (0–2000)

0.047

Education

 8th grade or less

40 (31%)

4 (44%)

36 (30%)

0.278

 At least some high school

73 (56%)

3 (33%)

70 (58%)

 More than high school

17 (13%)

2 (22%)

15 (12%)

Unemployed

73 (56%)

6 (67%)

67 (55%)

0.731

Number of HH members, by Self-Report (Median, IQR)

5 (3–6)

6 (5–6)

4 (3–6)

0.130

Number of HH Contacts Participating in Study (Median, IQR)

2 (1–3)

3 (2–6)

2 (1–3)

0.005

Years lived in HH (Median, IQR)

30 (20–40)

37 (28–43)

30 (19–39)

0.235

Previous TB

15 (12%)

1 (11%)

14 (12%)

1.0

TB Symptoms

 Cough

58 (45%)

4 (44%)

54 (45%)

1.0

 Fever

45 (35%)

1 (11%)

44 (36%)

0.162

 Fatigue

64 (49%)

4 (44%)

60 (50%)

1.0

 Loss of appetite

25 (19%)

1 (11%)

24 (20%)

1.0

 Weight loss

84 (65%)

5 (56%)

79 (65%)

0.720

 Night sweats

55 (42%)

5 (56%)

50 (41%)

0.493

 At least one TB symptom

112 (86%)

7 (78%)

105 (87%)

0.611

Symptom duration

 No symptoms

18 (14%)

2 (22%)

16 (13%)

0.357

  < 1 month

57 (44%)

3 (33%)

54 (45%)

 1–6 months

32 (25%)

1 (11%)

31 (26%)

  > 6 months

23 (18%)

3 (33%)

20 (17%)

Smear Positive (overall n = 60)**

44 (73%)

2 (29%)

42 (79%)

0.012

Xpert MTB/RIF Positive (overall n = 64)c

55 (86%)

2 (67%)

53 (87%)

0.370

  1. *Categorical variables were tested using Fisher’s Exact Test, and continuous variables were tested with the non-parametric Mann-Whitney test
  2. **70 individuals were missing smear results in the clinic TB register and/or index case TB card (68 index cases living in households with no new TB cases, and 2 individuals living in households with ≥1 new TB case)
  3. ***IQR: Interquartile range
  4. aIndex cases from households with at least one member diagnosed with laboratory confirmed TB as a part of this study
  5. bIndex cases from households with no members diagnosed with laboratory confirmed TB as a part of this study
  6. c66 individuals were missing Xpert results in the clinic TB register and/or index case TB card (60 index cases living in household with no new TB cases, and 6 individuals living in households with ≥1 new TB case)