Anaerobic coverage as definitive therapy does not affect clinical outcomes in community-onset bacteremic biliary tract infection without anaerobic bacteremia

Table 2 Univariate analysis of the association between different variables and treatment failure in patients with community-onset bacteremic BTIs

Variables	OR	95%CI	p value
Age	1.02	0.98–1.06	0.384
Sex	1.84	0.59–5.76	0.294
Microbiology
E.coli	0.48	0.16–1.41	0.180
K. pneumoniae	4.83	1.51–15.43	0.008
Other^a	0.59	0.17-2.01	0.398
Underlying disease
Liver cirrhosis	1.40	0.14–14.32	0.749
Diabetes mellitus	0.71	0.22–2.23	0.552
Congestive heart failure	1.04	0.30–3.63	0.953
Chronic obstructive pulmonary diseases	1.03	0.20–5.38	0.969
Chronic renal failure	5.54	0.69–44.79	0.108
Malignancy	4.90	1.54–15.59	0.007
Healthcare-associated bacteremia	4.06	1.29–12.83	0.017
Pitt bacteremia score	1.74	1.22–2.48	0.002
Appropriate empirical therapy	0.54	0.174–1.70	0.294
Definitive therapy without anti-anaerobic therapy	1.3	0.38–4.47	0.677
No drainage^b	0.54	0.15–2.0	0.357

^aOther pathogens included Enterococcus spp., Streptococcus spp., Enterobacter spp., Pseudomonas spp., Raoultella spp., Acinetobacter spp., Citrobacter spp., Aeromonas spp.
^bDrainage included endoscopic retrograde cholangiopancreatography, percutaneous transhepatic cholangial drainage, percutaneous transhepatic gallbladder drainage, surgical drainage and indwelling stent

ISSN: 1471-2334