Fig. 2From: Genetic structures of invasive Streptococcus pneumoniae isolates from Korean children obtained between 1995 and 2013Sequence type changes in the main genotypes CC320 (a), CC81 (b), and CC166 (c) across the study periods. In CC320, serotype 19A increased from 52.9 to 64.6%, and then to 92.0% (a). In CC81, serotype 23F decreased significantly, whereas serotypes 6A, 13, and 15A increased (b). The proportions of serotypes 9 V and 11A crossed over into CC166 during the study periods (c). PCV, pneumococcal conjugate vaccine; MLST, multilocus sequence typing; CC, clonal complex; S, singletonBack to article page