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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Delayed and highly specific antibody response to nonstructural protein 1 (NS1) revealed during natural human ZIKV infection by NS1-based capture ELISA

Fig. 4

Binding of DENV1-immune plasma to recombinant ZIKV and DENV1–4 NS1 proteins. A total of 108 sera (n = 35 for primary infection, n = 20 for secondary infection and n = 53 for unknown) from the DENV1-infected individuals were tested by ELISA for binding to NS1 proteins of ZIKV and DENV1–4 at a 1:100 dilution. Negative controls were plasma from healthy donors (n = 19). Each serum sample was tested in duplicates. Significance was analyzed by two-way ANOVA followed by Tukey’s multiple comparisons test correction

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