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Table 4 Univariate and multi-variate analysis of risk factor associated with 28-day mortality among patients with KP BSI

From: Risk factors for carbapenem-resistant K. pneumoniae bloodstream infection and predictors of mortality in Chinese paediatric patients

Variable

Survived (n = 126)

Died (n = 12)

Univariate analysis

Multi-variate analysis

OR (95% CI)

P

OR (95% CI)

P

Age (months), median (IQR)

24.23 (0.91–107.55)

32.41 (3.54–52.99)

–

0.919

–

–

Male

72 (57.1)

8 (66.7)

–

0.739

–

–

Underlying disease

106 (84.1)

12 (100)

–

0.214

–

–

Hematologic malignancies

60 (47.6)

6 (50.0)

–

0.875

–

–

Congenital anomalies

16 (12.7)

3 (25.0)

–

0.457

–

–

Prematurity

12 (9.5)

1 (8.3)

–

1.000

–

–

Malnutrition

6 (4.8)

1 (8.3)

–

1.000

–

–

Immunodeficiencies

6 (4.8)

0 (0)

–

1.000

–

–

Deep venous catheterization

97 (77.0)

11 (91.7)

–

0.417

–

–

Mechanical ventilation

10 (7.9)

7 (58.3)

16.240 (4.352–60.607)

< 0.001

9.502 (2.098–43.033)

0.003

Organ dysfunction

44 (34.9)

9 (75.0)

5.591 (1.439–21.718)

0.016

–

–

Septic shock

9 (7.1)

6 (50.0)

13.000 (3.476–48.623)

< 0.001

6.418 (1.342–30.686)

0.020

Empirical treatment active in vitro

76 (60.3)

5 (41.7)

–

0.233

–

–

Definitive treatment active in vitro a

100 (79.4)

5 (62.5)

–

0.370

–

–

Carbapenem-including treatment a

90 (71.4)

5 (62.5)

–

0.691

–

–

Isolation of CRKP

44 (34.9)

10 (83.3)

9.318 (1.955–44.421)

0.003

9.171 (1.546–54.416)

0.015

  1. a Four patients had died before blood culture results were available.
  2. P-values in bold italic shows variables with evidence of association in univariate and multi-variate analysis