Skip to main content

Table 4 Univariate and multi-variate analysis of risk factor associated with 28-day mortality among patients with KP BSI

From: Risk factors for carbapenem-resistant K. pneumoniae bloodstream infection and predictors of mortality in Chinese paediatric patients

Variable Survived (n = 126) Died (n = 12) Univariate analysis Multi-variate analysis
OR (95% CI) P OR (95% CI) P
Age (months), median (IQR) 24.23 (0.91–107.55) 32.41 (3.54–52.99) 0.919
Male 72 (57.1) 8 (66.7) 0.739
Underlying disease 106 (84.1) 12 (100) 0.214
Hematologic malignancies 60 (47.6) 6 (50.0) 0.875
Congenital anomalies 16 (12.7) 3 (25.0) 0.457
Prematurity 12 (9.5) 1 (8.3) 1.000
Malnutrition 6 (4.8) 1 (8.3) 1.000
Immunodeficiencies 6 (4.8) 0 (0) 1.000
Deep venous catheterization 97 (77.0) 11 (91.7) 0.417
Mechanical ventilation 10 (7.9) 7 (58.3) 16.240 (4.352–60.607) < 0.001 9.502 (2.098–43.033) 0.003
Organ dysfunction 44 (34.9) 9 (75.0) 5.591 (1.439–21.718) 0.016
Septic shock 9 (7.1) 6 (50.0) 13.000 (3.476–48.623) < 0.001 6.418 (1.342–30.686) 0.020
Empirical treatment active in vitro 76 (60.3) 5 (41.7) 0.233
Definitive treatment active in vitro a 100 (79.4) 5 (62.5) 0.370
Carbapenem-including treatment a 90 (71.4) 5 (62.5) 0.691
Isolation of CRKP 44 (34.9) 10 (83.3) 9.318 (1.955–44.421) 0.003 9.171 (1.546–54.416) 0.015
  1. a Four patients had died before blood culture results were available.
  2. P-values in bold italic shows variables with evidence of association in univariate and multi-variate analysis