From: Varicella zoster virus infections in neurological patients: a clinical study
Parameter | Trigeminal nerve ganglionitis with rash (n = 11) | Dorsal root ganglionitis with rash (n = 16) | Dorsal root ganglionitis with radiculitis (n = 5) | Facial nerve palsy (n = 19) | CNS infection (n = 34) |
---|---|---|---|---|---|
Pleocytosis (≥5 cells/μL) | 2 (18%) | 2 (13%) | 4 (80%) | 12 (63%) | 32 (94%) |
Lactate (≥3.5 mmol/L) | 0 | 0 | 0 | 1 (5%) | 3 (9%) |
Blood-CSF barrier dysfunction | 0 | 8 (50%) | 3 (60%) | 8 (42%) | 20 (59%) |
Intrathecal synthesis of immunoglobulins | 0 | 0 | 0 | 4 (21%) | 6 (18%) |
Isolated IgG | _ | _ | _ | 1 | _ |
Isolated IgA | _ | _ | _ | _ | _ |
Isolated IgM | _ | _ | _ | _ | _ |
Combined IgG + IgM | _ | _ | _ | _ | _ |
Combined IgG + IgA | _ | _ | _ | _ | 1 |
Combined IgM + IgA | _ | _ | _ | 2 | 1 |
Combined IgG + IgM + IgA | _ | _ | _ | 1 | 4 |
CSF oligoclonal bands | 1 (9%) | 0 | 1 (20%) | 7 (37%) | 11 (32%) |
PCR/VZV antibody synthesis | 0 | 2 (13%) | 3 (60%) | 12 (63%) | 34 (100%) |
PCR positive | _ | 1 | 1 | 3 | 23 |
VZV antibody synthesis | _ | 1 | 2 | 9 | 11 |