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Table 2 Performance evaluation of the CapitalBio™ DNA microarray for MDR-TB cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

From: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

  Conventional drug susceptibility testing        
CapitalBio™ DNA microarray MDR-TB (%) non-MDR (%) Total No. Sensitivity (%) Specificity (%) AR PPV (%) NPV (%) Kappa
     74.1 99.8 93.6 99.2 92.4 0.81
MDR-TB 120 (74.1) 1 (0.2) 121       
Non-MDR 42 (25.9) 508 (99.8) 550       
total 162 509 671       
  1. Abbreviations: PPV positive predictive value, NPV negative predictive value, AR agreement rate