“Tuberculosis in advanced HIV infection is associated with increased expression of IFNγ and its downstream targets”

Table 1 Demographic Characteristics and Participant Outcomes

	Total^a	TB-HIV	HIV	p-value
	(n = 32)	(n = 17)	(n = 15)	p-value
Female	62% (20/32)	47% (8/17)	80% (12/15)	0.08^
Median Age (range)	32 [18–53]	30 [18–52]	36 [24–53]	0.43^^
Initial CD4⁺ (cells/μL)	50 [4–105]^b	23 [4–105]	67 [11–96]	0.15^^
Time to ART start (days)	14 [6–80]^c	14.5 [12–80]	12 [6–51]	0.08^^
IRIS	20% (5/25)	45% (5/11)	0% (0/14)	0.13^
Alive at 6 months	75% (24/32)	59% (10/17)	93% (14/15)	0.03^

^aDemographic data available for 32 study participants. Whole blood RNA-Seq analysis done for 33 participants
^bThe initial CD4 count for 2 participants was 103 and 105 cells/μl; however when repeated for the study, the counts were less than 100 cells/μl
^c19 observations
^p-value calculated by Fischer’s exact
^^p-value calculated by Wilcoxon rank sum test
Age given is median age, range is entire range of ages. CD4⁺ range is entire range of CD4⁺ T cell counts

ISSN: 1471-2334