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Table 3 Expression of cell-surface expressed markers on CD4+ and CD8+ T lymphocytes

From: HBV and HIV viral load but not microbial translocation or immune activation are associated with liver fibrosis among patients in South Africa

 

Co-infected

HBV Mono

HIV Mono

Control

p

%CD4/CD38+/HLA-DR+

9.9 (6.2–17)

4.7 (3.6–6.3)

7 (4.5–12)

3.5 (2.6–6)

< 0.0001

%CD8/CD38+/HLA-DR+

30 (17–53)

17 (14–22)

23 (16–33)

16 (7.7–26)

< 0.0001

%CD4+/PD-1+

25 (18–34)

18 (13–23)

21 (15–27)

13 (8–22)

< 0.0001

%CD8+/PD-1+

22 (15–33)

13.2 (11–20)

22 (15–26)

15 (9–21)

< 0.0001

  1. Median and IQR (in parenthesis) are shown. Values are percentages of either CD4+ or CD8+ T cells expressing marker of interest