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Table 2 Adjusted analysis of factors associated with liver-related mortality among people with an HBV and HCV notification, NSW 1993-2012, n = 150,403

From: Mortality trends among people with hepatitis B and C: a population-based linkage study, 1993-2012

Characteristics, n % HBV HCV
Deceaseda   aHRb 95% CI P Deceaseda   aHRb 95% CI P
n = 582 % n = 2215 %
Birth cohort
 ≥ 1965 66 < 1 1.00 247 1 1.00
 1945-1964 304 1 6.19 4.72, 8.11 < 0.001 1542 4 7.33 6.39, 8.40 < 0.001
 ≤ 1944 212 5 28.07 21.02, 37.47 < 0.001 426 9 31.88 26.83, 37.87 < 0.001
Gender
 Female 102 < 1 1.00 559 2 1.00
 Male 477 2 2.65 2.13, 3.30 < 0.001 1654 3 1.47 1.33, 1.62 < 0.001
 Missing 3 1 1.44 0.45, 4.54 0.539 2 1 0.41 0.10, 1.64 0.208
Country of birthc
 Australia 109 2 1.00 1024 3 1.00
 Asia-Pacific 148 1 0.89 0.67, 1.19 0.425 130 3 1.07 0.88, 1.29 0.493
 Other 76 2 0.91 0.67, 1.25 0.580 311 5 1.43 1.25, 1.63 < 0.001
 Missing 249 1 0.86 0.66, 1.12 0.268 750 2 0.88 0.79, 0.97 0.015
Year of notification
  ≤ 2000 316 1 1.00 1347 3 1.00
 2001-2006 206 1 1.26 1.01, 1.58 0.041 627 2 1.48 1.32, 1.67 < 0.001
 2007-2012 60 < 1 1.44 1.01, 2.06 0.045 241 1 2.98 2.47, 3.60 < 0.001
HBV/HCV co-infection
 No 461 1 1.00 2094 2 1.00
 Yes 121 3 2.63 2.03, 3.41 < 0.001 121 3 1.53 1.28, 1.85 < 0.001
HIV co-infection
 No 572 1 1.00 2186 2 1.00
 Yes 10 3 3.46 1.83, 6.55 < 0.001 29 3 1.78 1.23, 2.57 0.002
Area of residence at the time of notification
 Rural 92 2 1.00
 Outer metropolitan 262 1 1.02 0.78, 1.32 0.899
 Metropolitan 227 1 0.84 0.65, 1.10 0.207
 Missing 1 < 1 0.21 0.03, 1.53 0.124
History of alcohol-use disorder
 No 448 1 1.00 1050 1 1.00
 Yes 134 7 6.98 5.54, 8.78 < 0.001 1165 7 8.30 7.56, 9.10 < 0.001
History of OSTd
 No 538 1 1.00 1675 3 1.00
 Yes 44 3 0.84 0.57, 1.25 0.391 540 2 0.92 0.82, 1.03 0.150
  1. aRecords included 2002-2013, badjusted hazard ratio, cmajority of countries included in the other category were European (HBV n = 50, HCV n = 229). Non-European countries were included in the other category given the small numbers (HBV n = 26, HCV n = 72), dincluded as a time-dependent variable