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Table 2 Adjusted analysis of factors associated with liver-related mortality among people with an HBV and HCV notification, NSW 1993-2012, nā€‰=ā€‰150,403

From: Mortality trends among people with hepatitis B and C: a population-based linkage study, 1993-2012

Characteristics, n %

HBV

HCV

Deceaseda

Ā 

aHRb

95% CI

P

Deceaseda

Ā 

aHRb

95% CI

P

nā€‰=ā€‰582

%

nā€‰=ā€‰2215

%

Birth cohort

ā€ƒā‰„ā€‰1965

66

<ā€‰1

1.00

ā€“

ā€“

247

1

1.00

ā€“

ā€“

ā€ƒ1945-1964

304

1

6.19

4.72, 8.11

<ā€‰0.001

1542

4

7.33

6.39, 8.40

<ā€‰0.001

ā€ƒā‰¤ā€‰1944

212

5

28.07

21.02, 37.47

<ā€‰0.001

426

9

31.88

26.83, 37.87

<ā€‰0.001

Gender

ā€ƒFemale

102

<ā€‰1

1.00

ā€“

ā€“

559

2

1.00

ā€“

ā€“

ā€ƒMale

477

2

2.65

2.13, 3.30

<ā€‰0.001

1654

3

1.47

1.33, 1.62

<ā€‰0.001

ā€ƒMissing

3

1

1.44

0.45, 4.54

0.539

2

1

0.41

0.10, 1.64

0.208

Country of birthc

ā€ƒAustralia

109

2

1.00

ā€“

ā€“

1024

3

1.00

ā€“

ā€“

ā€ƒAsia-Pacific

148

1

0.89

0.67, 1.19

0.425

130

3

1.07

0.88, 1.29

0.493

ā€ƒOther

76

2

0.91

0.67, 1.25

0.580

311

5

1.43

1.25, 1.63

<ā€‰0.001

ā€ƒMissing

249

1

0.86

0.66, 1.12

0.268

750

2

0.88

0.79, 0.97

0.015

Year of notification

ā€ƒā€‰ā‰¤ā€‰2000

316

1

1.00

ā€“

ā€“

1347

3

1.00

ā€“

ā€“

ā€ƒ2001-2006

206

1

1.26

1.01, 1.58

0.041

627

2

1.48

1.32, 1.67

<ā€‰0.001

ā€ƒ2007-2012

60

<ā€‰1

1.44

1.01, 2.06

0.045

241

1

2.98

2.47, 3.60

<ā€‰0.001

HBV/HCV co-infection

ā€ƒNo

461

1

1.00

ā€“

ā€“

2094

2

1.00

ā€“

ā€“

ā€ƒYes

121

3

2.63

2.03, 3.41

<ā€‰0.001

121

3

1.53

1.28, 1.85

<ā€‰0.001

HIV co-infection

ā€ƒNo

572

1

1.00

ā€“

ā€“

2186

2

1.00

ā€“

ā€“

ā€ƒYes

10

3

3.46

1.83, 6.55

<ā€‰0.001

29

3

1.78

1.23, 2.57

0.002

Area of residence at the time of notification

ā€ƒRural

92

2

1.00

ā€“

ā€“

ā€“

ā€“

ā€“

ā€“

ā€“

ā€ƒOuter metropolitan

262

1

1.02

0.78, 1.32

0.899

ā€“

ā€“

ā€“

ā€“

ā€“

ā€ƒMetropolitan

227

1

0.84

0.65, 1.10

0.207

ā€“

ā€“

ā€“

ā€“

ā€“

ā€ƒMissing

1

<ā€‰1

0.21

0.03, 1.53

0.124

ā€“

ā€“

ā€“

ā€“

ā€“

History of alcohol-use disorder

ā€ƒNo

448

1

1.00

ā€“

ā€“

1050

1

1.00

ā€“

ā€“

ā€ƒYes

134

7

6.98

5.54, 8.78

<ā€‰0.001

1165

7

8.30

7.56, 9.10

<ā€‰0.001

History of OSTd

ā€ƒNo

538

1

1.00

ā€“

ā€“

1675

3

1.00

ā€“

ā€“

ā€ƒYes

44

3

0.84

0.57, 1.25

0.391

540

2

0.92

0.82, 1.03

0.150

  1. aRecords included 2002-2013, badjusted hazard ratio, cmajority of countries included in the other category were European (HBV nā€‰=ā€‰50, HCV nā€‰=ā€‰229). Non-European countries were included in the other category given the small numbers (HBV nā€‰=ā€‰26, HCV nā€‰=ā€‰72), dincluded as a time-dependent variable