Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

Ning, Nian-zhi; Li, Tao; Zhang, Ju-ling; Qu, Fen; Huang, Jie; Liu, Xiong; Li, Zhan; Geng, Wei; Fu, Jun-liang; Huan, Wang; Zhang, Shu-yong; Bao, Chun-mei; Wang, Hui

doi:10.1186/s12879-018-3101-1

BMC Infectious Diseases

Table 5 Risk factors for 30-day mortality in patients with SBP

From: Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

	Survivors (n = 303)	Nonsurvivors (n = 105)	Univariate analysis		Multivariate analysis
	Survivors (n = 303)	Nonsurvivors (n = 105)	HR (95% Cl)	P	HR (95% Cl)	p
Age(yr)	52.1 ± 11.5	55.9 ± 11.7	1.025 (1.008–1.041)	0.003	1.021 (1.003–1.04)	0.022
Sex (male)	245 (80.9%)	76 (72.4%)	1.326 (0.864–2.035)	0.196	–	–
Nosocomial infection	134 (44.2%)	69 (65.7%)	2.311 (1.544–3.46)	< 0.001	1.577 (0.946–2.627)	0.081
MELD score	18.7 ± 8.4	29.1 ± 9.5	1.1 (1.078–1.122)	< 0.001	1.067 (1.04–1.095)	< 0.001
Days between admission and onset of infection	2(0–7)	8(1–18.5)	1.028 (1.016–1.039)	< 0.001	1.015 (0.999–1.032)	0.07
Symptoms of peritonitis	259 (85.5%)	81 (77.1%)	0.672 (0.426–1.06)	0.088	–	–
ALT(U/L)	36 (21–63)	57 (25–150.5)	1.001 (1–1.001)	0.002	1.001 (1.000–1.002)	0.310
AST(U/L)	59 (37–100)	95 (48–202.5)	1 (1–1.001)	< 0.001	1.000 (1.000–1.001)	0.728
Prealbumin(mg/L)	46.8 ± 25.9	33.7 ± 22.9	0.98 (0.971–0.989)	< 0.001	0.999 (0.989–1.009)	0.791
Bun(mmol/L)	8 (5.1–11.9)	13.3 (8.1–20.8)	1.061 (1.043–1.078)	< 0.001	0.998(0.977–1.019)	0.824
Serum PMN (cells/μL)	5.8 (3.5–9.2)	7.5 (3.8–12.2)	1.061 (1.032–1.091)	< 0.001	1.001(0.97–1.034)	0.931
Total Protein(g/L)	55 (49–60)	51 (44–57.5)	0.979(0.967–0.991)	0.001	1.002 (0.988–1.016)	0.778
Ascitic PMN(cells/μL)	2760 (741.4–7821)	3717.2 (660.9–8356)	1 (1–1)	0.241	–	–
Hepatocellular carcinoma	83 (27.4%)	43 (41%)	1.874 (1.268–2.771)	0.002	1.755 (1.14–2.703)	0.011
Hepatic encephalopathy	80 (26.4%)	65 (61.9%)	3.282 (2.213–4.866)	< 0.001	1.533(0.972–2.42)	0.066
Septic shock	24 (7.9%)	65 (61.9%)	7.624 (5.135–11.321)	< 0.001	4.169 (2.599–6.686)	< 0.001
Gastrointestinal haemorrhage	47 (15.5%)	33 (31.4%)	2.02 (1.337–3.05)	0.001	1.243 (0.798–1.936)	0.337
Diabetes mellitus	48 (15.8%)	16 (15.2%)	1.044 (0.613–1.778)	0.875	–	–

P-values < 0.05 and corresponding HR are indicated in bold

Back to article page

ISSN: 1471-2334

Contact us

Submission enquiries: bmcinfectiousdiseases@biomedcentral.com
General enquiries: ORSupport@springernature.com