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Table 5 Risk factors for 30-day mortality in patients with SBP

From: Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

  Survivors
(n = 303)
Nonsurvivors
(n = 105)
Univariate analysis   Multivariate analysis
HR (95% Cl) P HR (95% Cl) p
Age(yr) 52.1 ± 11.5 55.9 ± 11.7 1.025 (1.008–1.041) 0.003   1.021 (1.003–1.04) 0.022
Sex (male) 245 (80.9%) 76 (72.4%) 1.326 (0.864–2.035) 0.196  
Nosocomial infection 134 (44.2%) 69 (65.7%) 2.311 (1.544–3.46) < 0.001   1.577 (0.946–2.627) 0.081
MELD score 18.7 ± 8.4 29.1 ± 9.5 1.1 (1.078–1.122) < 0.001   1.067 (1.04–1.095) < 0.001
Days between admission and onset of infection 2(0–7) 8(1–18.5) 1.028 (1.016–1.039) < 0.001   1.015 (0.999–1.032) 0.07
Symptoms of peritonitis 259 (85.5%) 81 (77.1%) 0.672 (0.426–1.06) 0.088  
ALT(U/L) 36 (21–63) 57 (25–150.5) 1.001 (1–1.001) 0.002   1.001 (1.000–1.002) 0.310
AST(U/L) 59 (37–100) 95 (48–202.5) 1 (1–1.001) < 0.001   1.000 (1.000–1.001) 0.728
Prealbumin(mg/L) 46.8 ± 25.9 33.7 ± 22.9 0.98 (0.971–0.989) < 0.001   0.999 (0.989–1.009) 0.791
Bun(mmol/L) 8 (5.1–11.9) 13.3 (8.1–20.8) 1.061 (1.043–1.078) < 0.001   0.998(0.977–1.019) 0.824
Serum PMN (cells/μL) 5.8 (3.5–9.2) 7.5 (3.8–12.2) 1.061 (1.032–1.091) < 0.001   1.001(0.97–1.034) 0.931
Total Protein(g/L) 55 (49–60) 51 (44–57.5) 0.979(0.967–0.991) 0.001   1.002 (0.988–1.016) 0.778
Ascitic PMN(cells/μL) 2760 (741.4–7821) 3717.2 (660.9–8356) 1 (1–1) 0.241  
Hepatocellular carcinoma 83 (27.4%) 43 (41%) 1.874 (1.268–2.771) 0.002   1.755 (1.14–2.703) 0.011
Hepatic encephalopathy 80 (26.4%) 65 (61.9%) 3.282 (2.213–4.866) < 0.001   1.533(0.972–2.42) 0.066
Septic shock 24 (7.9%) 65 (61.9%) 7.624 (5.135–11.321) < 0.001   4.169 (2.599–6.686) < 0.001
Gastrointestinal haemorrhage 47 (15.5%) 33 (31.4%) 2.02 (1.337–3.05) 0.001   1.243 (0.798–1.936) 0.337
Diabetes mellitus 48 (15.8%) 16 (15.2%) 1.044 (0.613–1.778) 0.875  
  1. P-values < 0.05 and corresponding HR are indicated in bold