Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

Ning, Nian-zhi; Li, Tao; Zhang, Ju-ling; Qu, Fen; Huang, Jie; Liu, Xiong; Li, Zhan; Geng, Wei; Fu, Jun-liang; Huan, Wang; Zhang, Shu-yong; Bao, Chun-mei; Wang, Hui

doi:10.1186/s12879-018-3101-1

BMC Infectious Diseases

Table 4 Risk factors for 30-day mortality in patients with BA

From: Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

	Survivors (n = 166)	Nonsurvivors (n = 26)	Univariate analysis		Multivariate analysis
	Survivors (n = 166)	Nonsurvivors (n = 26)	HR (95% Cl)	P	HR (95% Cl)	p
Age (yr)	55.3 ± 12.2	58.3 ± 11.6	1.022(0.991–1.055)	0.162	–	–
Sex (male)	125 (75.3%)	19 (73.1%)	1.152 (0.484–2.742)	0.750	–	–
Nosocomial infection	68 (41%)	16 (61.5%)	2.21 (1.000–4.884)	0.050	–	–
MELD score	14.7 ± 6.8	26.1 ± 7.7	1.153 (1.102–1.207)	< 0.001	1.054 (0.988–1.125)	0.108
Days between admission and onset of infection	2(0–6)	4.5(0–17.3)	1.022 (1.002–1.042)	0.027	1.015 (0.986–1.045)	0.301
Symptoms of peritonitis	102 (61.4%)	16 (61.5%)	0.915 (0.414–2.022)	0.826	–	–
ALT(U/L)	28.0 (19.0–46.0)	45.5 (28.0–93.3)	1.003(1.000–1.006)	0.036	1.001(0.992–1.009)	0.861
AST(U/L)	50.0 (32.0–75.5)	88.0 (51.5–180.8)	1.003(1.001–1.005)	0.002	1.003(0.997–1.008)	0.308
Prealbumin(mg/L)	57.3 ± 24.2	42.6 ± 17.8	0.975 (0.957–0.993)	0.006	0.981 (0.958–1.004)	0.100
Bun(mmol/L)	5.9(4.7–9.1)	11.5 (7.7–15.5)	1.099 (1.055–1.143)	< 0.001	1.1 (1.033–1.173)	0.003
Serum PMN (cells/μL)	3.6 (2.1–5.8)	6.5 (5.2–12.6)	1.219 (1.124–1.322)	< 0.001	1.027 (0.926–1.14)	0.609
Total Protein(g/L)	57.0 (52.0–64.0)	51.0 (47.0–54.0)	0.979(0.957–1.001)	0.060	–	–
Ascitic PMN(cells/μL)	24.0 (6.5–69.0)	13.0 (3.2–115.0)	1.002 (0.996–1.008)	0.589	–	–
Hepatocellular carcinoma	42 (25.3%)	7 (26.9%)	1.056 (0.443–2.514)	0.903	–	–
Hepatic encephalopathy	39 (23.5%)	19 (73.1%)	6.442 (2.704–15.346)	< 0.001	2.382 (0.849–6.679)	0.099
Septic shock	8 (4.8%)	11 (42.3%)	5.725 (2.614–12.536)	< 0.001	2.247 (0.876–5.762)	0.092
Gastrointestinal haemorrhage	23 (13.9%)	11 (42.3%)	2.966 (1.361–6.466)	0.006	1.705 (0.655–4.438)	0.274
Diabetes mellitus	34 (20.5%)	3 (11.5%)	0.576 (0.1730–1.920)	0.369	–	–

P-values < 0.05 and corresponding HR are indicated in bold

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