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Table 3 Risk factors for BA episodes progressing to SBP

From: Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

  Progress to SBP (n = 45) No progress to SBP (n = 142) Univariate analysis   Multivariate analysis
P Odds ratio (95% CI) P Odds ratio (95% CI)
Sex (male) 37 (82.2%) 108 (76.1%) 0.390 0.687 (0.292–1.616)  
Age (yr) 52.4 ± 9.2 55.4 ± 12.5 0.144 0.979(0.951–1.007)  
Nosocomial infection 23 (51.1%) 57 (40.1%) 0.197 1.559 (0.795–3.059)  
MELD score 23.0 ± 10.7 16.3 ± 7.4 < 0.001 1.089 (1.046–1.133)   0.503 1.036 (0.934–1.149)
Days between admission and onset of infection 3 (0–7.5) 1 (0–6) 0.239 1.018 (0.989–1.048)  
Fever 30 (66.7%) 69 (48.6%) 0.036 2.116 (1.049–4.268)   0.053 2.533 (0.986–6.505)
Chills 4 (8.9%) 11 (7.7%) 0.806 1.162 (0.351–3.846)  
Abdominal pain 15(33.3%) 34 (23.9%) 0.214 1.588(0.765–3.295)  
ALT(U/L) 42.0 (24.0–106.0) 30.0 (20.0–49.0) 0.011 1.005 (1.001–1.009)   0.326 1.004 (0.996–1.011)
AST(U/L) 70.0 (42.0–135.5) 52.5 (33.0–88.5) 0.030 1.003(1.000–1.005)   0.602 1.001(0.996–1.006)
Prealbumin(mg/L) 41.3 ± 22.7 56.1 ± 24.8 0.001 0.973 (0.957–0.989)   0.224 0.986 (0.965–1.008)
Prothrombin time(S) 19.2 (15.7–31.1) 16.3 (14.1–19.3) < 0.001 1.078 (1.034–1.125)   0.118 1.064 (0.984–1.149)
Bun(mmol/L) 8.6 (5.5–13.9) 6.6 (4.8–11.5) 0.074 1.039 (0.996–1.083)  
Serum PMN(cells/μL) 4.9 (2.8–9.8) 4.2 (2.4–6.6) 0.002 1.12 (1.042–1.205)   0.161 1.641 (0.822–3.277)
Serum WBC(cells/μL) 6.1 (4.0–11.8) 5.4 (3.6–8.5) 0.006 1.096 (1.027–1.17)   0.223 0.671 (0.353–1.275)
Serum creatinine (μmol/L) 105.0 (82.0–159.0) 88.5 (70.8–113.5) 0.15 1.003 (0.999–1.006)  
Total protein(g/L) 56.0 (50.0–61.0) 55.0 (50.0–63.0) 0.679 0.997 (0.983–1.011)  
Total bilirubin (μmol/L) 98.5 (43.9–311.4) 51.9 (32.4–140.2) 0.018 1.002 (1.000–1.005)   0.36 0.998 (0.994–1.002)
Ascitic PMN(cells/μL) 64.7 (21.7–141.7) 24.0 (5.3–74.8) 0.002 1.008 (1.003–1.013)   0.029 1.007 (1.001–1.013)
Ascitic WBC(cells/μL) 257.0(114.5–370.0) 161.0 (91.8–302.8) 0.529 1.000(0.999–1.002)  
hepatocellular carcinoma 20 (44.4%) 39 (27.5%) 0.035 2.113 (1.056–4.229)   0.024 3.047 (1.161–7.997)
hepatic encephalopathy 16(35.6%) 43(30.3%) 0.508 1.27(0.626–2.577)  
septic shock 12(26.7%) 16 (11.3%) 0.014 2.864 (1.235–6.639)   0.799 0.851 (0.246–2.949)
Gastrointestinal haemorrhage 11 (24.4%) 29 (20.4%) 0.567 1.261 (0.57–2.786)  
diabetes mellitus 7 (15.6%) 28(19.7%) 0.534 0.75 (0.303–1.856)  
  1. P-values < 0.05 and corresponding Odds ratio are indicated in bold