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Table 3 Risk factors for BA episodes progressing to SBP

From: Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

 

Progress to SBP (n = 45)

No progress to SBP (n = 142)

Univariate analysis

 

Multivariate analysis

P

Odds ratio (95% CI)

P

Odds ratio (95% CI)

Sex (male)

37 (82.2%)

108 (76.1%)

0.390

0.687 (0.292–1.616)

 

Age (yr)

52.4 ± 9.2

55.4 ± 12.5

0.144

0.979(0.951–1.007)

 

Nosocomial infection

23 (51.1%)

57 (40.1%)

0.197

1.559 (0.795–3.059)

 

MELD score

23.0 ± 10.7

16.3 ± 7.4

< 0.001

1.089 (1.046–1.133)

 

0.503

1.036 (0.934–1.149)

Days between admission and onset of infection

3 (0–7.5)

1 (0–6)

0.239

1.018 (0.989–1.048)

 

Fever

30 (66.7%)

69 (48.6%)

0.036

2.116 (1.049–4.268)

 

0.053

2.533 (0.986–6.505)

Chills

4 (8.9%)

11 (7.7%)

0.806

1.162 (0.351–3.846)

 

Abdominal pain

15(33.3%)

34 (23.9%)

0.214

1.588(0.765–3.295)

 

ALT(U/L)

42.0 (24.0–106.0)

30.0 (20.0–49.0)

0.011

1.005 (1.001–1.009)

 

0.326

1.004 (0.996–1.011)

AST(U/L)

70.0 (42.0–135.5)

52.5 (33.0–88.5)

0.030

1.003(1.000–1.005)

 

0.602

1.001(0.996–1.006)

Prealbumin(mg/L)

41.3 ± 22.7

56.1 ± 24.8

0.001

0.973 (0.957–0.989)

 

0.224

0.986 (0.965–1.008)

Prothrombin time(S)

19.2 (15.7–31.1)

16.3 (14.1–19.3)

< 0.001

1.078 (1.034–1.125)

 

0.118

1.064 (0.984–1.149)

Bun(mmol/L)

8.6 (5.5–13.9)

6.6 (4.8–11.5)

0.074

1.039 (0.996–1.083)

 

Serum PMN(cells/μL)

4.9 (2.8–9.8)

4.2 (2.4–6.6)

0.002

1.12 (1.042–1.205)

 

0.161

1.641 (0.822–3.277)

Serum WBC(cells/μL)

6.1 (4.0–11.8)

5.4 (3.6–8.5)

0.006

1.096 (1.027–1.17)

 

0.223

0.671 (0.353–1.275)

Serum creatinine (μmol/L)

105.0 (82.0–159.0)

88.5 (70.8–113.5)

0.15

1.003 (0.999–1.006)

 

Total protein(g/L)

56.0 (50.0–61.0)

55.0 (50.0–63.0)

0.679

0.997 (0.983–1.011)

 

Total bilirubin (μmol/L)

98.5 (43.9–311.4)

51.9 (32.4–140.2)

0.018

1.002 (1.000–1.005)

 

0.36

0.998 (0.994–1.002)

Ascitic PMN(cells/μL)

64.7 (21.7–141.7)

24.0 (5.3–74.8)

0.002

1.008 (1.003–1.013)

 

0.029

1.007 (1.001–1.013)

Ascitic WBC(cells/μL)

257.0(114.5–370.0)

161.0 (91.8–302.8)

0.529

1.000(0.999–1.002)

 

hepatocellular carcinoma

20 (44.4%)

39 (27.5%)

0.035

2.113 (1.056–4.229)

 

0.024

3.047 (1.161–7.997)

hepatic encephalopathy

16(35.6%)

43(30.3%)

0.508

1.27(0.626–2.577)

 

septic shock

12(26.7%)

16 (11.3%)

0.014

2.864 (1.235–6.639)

 

0.799

0.851 (0.246–2.949)

Gastrointestinal haemorrhage

11 (24.4%)

29 (20.4%)

0.567

1.261 (0.57–2.786)

 

diabetes mellitus

7 (15.6%)

28(19.7%)

0.534

0.75 (0.303–1.856)

 

  1. P-values < 0.05 and corresponding Odds ratio are indicated in bold