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Table 3 Mutations distribution

From: The magnitude of antibiotic resistance to Helicobacter pylori in Africa and identified mutations which confer resistance to antibiotics: systematic review and meta-analysis

DRUGS

Isolates tested for mutations

Total mutation detected

Type of Mutations

Frequency (%)

CLARITHROMYCIN

334

97

A2143G

49(50.5%)

A2142G

24 (25%)

A2147G

17(17.5%)

A2146C

1 (1%)

A2142C

2(2%)

A2144G

2(2%)

A2143C

2(2%)

QUINOLONES

60

40

D87I

16 (40%)

D91N

14 (35%)

D91G

1(2.5%)

D91Y

1(2.5%)

N87 K

8 (20%)

METRONIDAZOLE

66

56

RdxA (41)

41(73.2%)

FrxA (15)

15(26.8%)

TETRACYCLINE

40

1

AGA926-928

1 (100%)