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Table 2 Application of 2016 Chinese CAP guideline in hospitalized patients over 65 years without risk factors of Pseudomonas aeruginosa infection (n = 2258)

From: Effects of age, comorbidity and adherence to current antimicrobial guidelines on mortality in hospitalized elderly patients with community-acquired pneumonia

Regimen General ward inpatients (n = 2090) ICU patients (n = 168)
Consistent with guideline 795(38.0) 1(0.6)
 β-lactam 415(19.8) 0(0)
 Fluoroquinolone 312(14.9) 0(0)
 β-lactam + macrolide 68(3.3) 0(0)
 β-lactam + fluoroquinolone 0(0) 1(0.6)
Undertreated by guideline 201(9.6) 120(71.4)
 β-lactam 153(7.3) a 92(54.8)b
 β-lactam + macrolide 21(1.0)a 1(0.6)
 Macrolide 15(0.7) 0(0)
 Fluoroquinolone +/− β-lactamc 0(0) 26(15.5)
 Other combination 12(0.6) 1(0.6)
Overtreated by guideline 1094(52.3) 47(28.0)
 Antipseudomonal β-lactamd 530(25.4)# 0(0)
 Fluoroquinolone +β-lactam/ othere 451(21.6) ## 37(22.0)*
 Antipseudomonal β-lactamd + macrolide 46(2.2) ### 5(3.0)**
 Antipseudomonal β-lactamd + othere 39(1.9) #### 2(1.2) ***
 Fluoroquinolone + macrolide 12(0.6) 0(0)
 β-lactam +quinolone+ othere 8(0.3) 3(1.8) ****
 β-lactam +macrolide+ fluoroquinolone /othere 8(0.3) 0(0)
  1. Data on empirical antimicrobial regimens in 37 patients were missing. Three patients in the general ward who were administered antifungal agents, and 6 patients in the ICU who were administered antipseudomonal β-lactam plus antifungal agents were ruled out
  2. β-lactama = penicillin, first / second generation cephalosporins
  3. β-lactamb = second/ third generation cephalosporins (n = 5), cephamycins (n = 12) and antipseudomonal β-lactam (n = 75, including carbapenem 25)
  4. β-lactamc = second generation cephalosporins (n = 6) and cephamycins (n = 7)
  5. Antipseudomonal β-lactamd = piperacillin/tazobactam, ticarcillin/clavulanic acid, mezlocillin/sulbactam, cefoperazone/sulbactam, ceftazidime, cefoperazone, cefepime, carbapenem (imipenem / cilastatin and meropenem)
  6. othere = imidazoles, tetracyclines, aminoglycoside, lincomycin, fosfomycin and glycopeptides
  7. # carbapenem = 108
  8. ## Antipseudomonal β-lactam = 260 (carbapenem = 36), other β-lactam = 182, othere = 9
  9. ### carbapenem = 11
  10. #### carbapenem+glycopeptide =6, carbapenem+other =6, other antipseudomonal β-lactam+other =27
  11. * Antipseudomonal β-lactam = 36 (carbapenem = 10); ** carbapenem = 2
  12. *** carbapenem+glycopeptide = 2; **** carbapenem = 2