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Table 1 Characteristics of hospitalized CAP patients over 65 years by age group (n = 3131)

From: Effects of age, comorbidity and adherence to current antimicrobial guidelines on mortality in hospitalized elderly patients with community-acquired pneumonia

Characteristics 65–74 y (n = 1134) 75–84 y (n = 1449) ≥ 85 y (n = 548)
Age(years, n = 3131) 66.43 ± 2.87 79.43 ± 2.78 88.54 ± 3.38
Male sex(n = 3131) 633(55.8) 791(54.6) 281(51.3)
Aspiration(n = 3131) 72(6.3) 141(9.7) 110(20.1)
Long-term bedridden status(n = 3131) 57(5.0) 117(8.1) 92(16.8)
Underlying conditions(n = 3131) 998(88.0) 1318(91.0) 521(95.1)
 Cardiovascular disease 615 (54.2) 935(64.5) 400(73.0)
  Hypertension 488(43.0) 749(51.7) 302(55.1)
  Ischemic heart disease 263(23.2) 493(34.0) 244(44.5)
  Congestive heart failure 65(5.7) 101(7.0) 35(6.4)
 Chronic respiratory disease 359(31.7) 391(27.0) 125(22.8)
  COPD 210(18.5) 275(19.0) 94(17.2)
  Bronchiectasis 153(13.5) 112(7.7) 36(6.6)
  Asthma 85(7.5) 29(4.4) 13(2.4)
 Cerebral vascular disease 191(16.8) 412(28.4) 211(38.5)
 Diabetes mellitus 224(19.8) 316(21.8) 111(20.3)
 Malignancy 90(7.9) 122(8.4) 40(7.3)
 Chronic renal disease 47(4.1) 76(5.2) 32(5.8)
 Dementia 8(0.7) 24(1.7) 24(4.4)
 Chronic liver disease 15(1.3) 20(1.4) 4(0.7)
History of hospitalization for CAP in previous year 80(7.1) 124(8.6) 59(10.8)
HCAP (n = 3131) 195(17.2) 231(15.9) 100(18.2)
Immunocompromisea (n = 3131) 37(3.3) 27(1.9) 6(1.1)
Multilobe infiltration (n = 3131) 458(40.4) 676(46.7) 273(49.8)
Pleural effusion (n = 3131) 221 (19.5) 387(26.7) 176(32.1)
CURB-65 (n = 3025 b)
 1 711(64.9) 769(55.6) 234(42.7)
 2 322(29.4) 455(32.9) 198(36.1)
 3–5 62(5.7) 158(11.4) 116(21.2)
PSI (n = 1714 c)
 I-III 453(73.7) 395(49.8) 84(27.5)
 IV 131(21.3) 320(40.4) 149(48.7)
 V 31(5.0) 78(9.8) 73(23.9)
Need for MV (n = 3131) 87(7.7) 129(8.9) 57(10.4)
 Non-invasive MV 62(5.5) 91(6.3) 40(7.3)
 invasive MV 42(3.7) 52(3.6) 23(4.2)
ICU admission(n = 3131) 68(6.0) 126(8.7) 75(13.7)
Outcome
 Hospital LOS (days) (n = 3131) 12.73 ± 9.62 13.29 ± 9.61 15.21 ± 12.78
 In-hospital mortality(n = 3131) 36(3.2) 78(5.4) 65(11.9)
 60-day mortality(n = 3011d) 53(4.7) 97(6.7) 77(14.1)
  1. Abbreviations: COPD chronic obstructive pulmonary disease, HCAP healthcare-associated pneumonia, PSI pneumonia severity index, MV mechanical ventilation, ICU intensive care unit, LOS length of stay
  2. adefined as (1) solid-organ transplant recipients; (2) stem cell transplant recipients or bone marrow transplantation within one year of admission, or at any time following transplantation for those with graft versus host disease; (3) patients undergoing chemotherapy for hematological diseases or solid-tumor malignancies within six months of admission, or neutropenia < 500 cells·m−3; (4) chest radiation therapy within one month of admission; (5)autoimmune disease receiving immunosuppressive therapy within three months of admission (i.e., oral prednisonean  ≥ 10 mg•d-1 for more than 3 weeks or the equivalent); (6) splenectomy
  3. b Figure of urea nitrogen was missing in 106 cases
  4. c The total number of patients with a complete data of PSI score
  5. d Loss to follow-up for patients was 62 cases. Data on empirical antimicrobial regimens in 49 patients were missing. 3 patients in general ward administered antifungal agents and 6 patients in ICU administered antipseudomonal β-lactam plus antifungal agents were ruled out