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Table 4 Data for hospitalization and risk factors, by type of discharge (N = 115)

From: Evaluation of Candida bloodstream infection and antifungal utilization in a tertiary care hospital

  Discharge (N = 56) In-hospital mortality (N = 59) OR (95% CI) P value
Gender
Female 23 (41.1) 21 (35.6) 1.00  
Male 33 (58.9) 38 (64.4) 1.26 (0.59; 2.69) 0.546
Age (years)    1.03 (1.01; 1.05) 0.015
Mean (SD) 63.80 (19.33) 72.03 (15.53)   
Median [1st Q - 3rd Q] 65.00 [50–81.50] 76.00 [60–85]   
Length of stay (days)    1.00 (1.00; 1.00) 0.952
Mean (SD) 69.02 (140.67) 70.58 (137.32)   
Median [1st Q - 3rd Q] 32 [20.25–64.25] 36 [23.50–56]   
Time to start empiric therapy with antifungal after blood culture
 Within 24 h 23 (41.1) 28 (47.5) 1.00  
 More than 24 h 27 (48.2) 21 (35.6) 0.64 (0.29; 1.41) 0.268
 No use of antifungal drug 6 (10.7) 10 (16.9) 1.37 (0.44; 4.56) 0.593
Used antimicrobial
 No 1 (1.8) 1 (1.7) 1.00  
 Yes 55 (98.2) 58 (98.3) - 11-22-2016 17:19:0 s2 0.970
Used chemotherapy
 No 52 (92.9) 51 (86.4) 1.00  
 Yes 4 (7.1) 8 (13.6) 2.04 (0.60; 8.03) 0.268
Used corticosteroid
 No 15 (26.8) 5 (8.5) 1.00  
 Yes 41 (73.2) 54 (91.5) 3.95 (1.40; 12.96) 0.014
Used parenteral nutrition
 No 37 (66.1) 32 (54.2) 1.00  
 Yes 19 (33.9) 27 (45.8) 1.64 (0.78; 3.53) 0.197
Used some type of central venous catheter
 No 22 (39.3) 7 (11.9) 1.00  
 Yes 34 (60.7) 52 (88.1) 4.81 (1.93; 13.30) 0.001
Had any type of surgery
 No 20 (35.7) 16 (27.1) 1.00  
 Yes 36 (64.3) 43 (72.9) 1.49 (0.68; 3.33) 0.322
Stayed at the intensive care unit
  No 17 (30.4) 4 (6.8) 1.00  
 Yes 39 (69.6) 55 (93.2) 5.99 (2.04; 22.07) 0.003
Length of stay in the intensive care unit (days) (n = 94)    1.04 (1.02; 1.06) 0.001
 Mean (SD) 16.03 (16.86) 28.42 (25.86)   
 Median [1st Q - 3rd Q] 10.00 (5.00–17.50) 23.00 (7.50–36.00)   
Neutropenia
 No 54 (96.4) 55 (93.2) 1.00  
 Yes 2 (3.6) 4 (6.8) 1.96 (0.37; 14.59) 0.447
Used vasoactive drug
 No 23 (41.1) 6 (10.2) 1.00  
 Yes 33 (58.9) 53 (89.8) 6.16 (2.39; 18.12) < 0.001
Used mechanical ventilation
 No 26 (46.4) 7 (11.9) 1.00  
 Yes 30 (53.6) 52 (88.1) 6.44 (2.61; 17.74) < 0.001
Hemodialysis
 No 45 (80.4) 32 (54.2) 1.00  
 Yes 11 (19.6) 27 (45.8) 3.45 (1.53; 8.21) 0.004
Blood transfusion
 No 48 (85.7) 40 (67.8) 1.00  
 Yes 8 (14.3) 19 (32.2) 2.85 (1.16; 7.55) 0.027
Positive blood culture even when using antifungal therapy
 No 44 (78.6) 36 (61.0) 1.00  
 Yes 12 (21.4) 23 (39.0) 2.34 (1.04; 5.48) 0.043
  1. Category variables presented by absolute and relative frequencies. Q quartile SD standard deviation, OR odds ratio obtained by simple logistic regression model (values, 1.00 for the reference categories) and, in parentheses, the 95% Confidence Interval (95% CI)