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Table 4 Clustering of agr locus mutations among clones and agr genotypes

From: Sub-inhibitory concentrations of oxacillin modify the expression of agr locus in Staphylococcus aureus clinical strains belonging to different clonal complexes

    agrB agrD agrC agrA  
Strain CC a agr group SNP b (N°) Non-synonymous predicted result SNP (N°) Non-synonymous predicted result SNP (N°) Non-synonymous predicted result SNP (N°) Non-synonymous predicted result Reference
SA_123 CC45 1 35 t329c (110 Ile > Thr);
g340t (114 Val > Phe);
t346g (116 Ser > Ala); t349a (117 Leu > Ile);
gta355ttg (119 Val > Leu);
tca361att (121 Ser > Ile);
gt364aa (122 Val > Lys);
c452t (151 Thr > Ile);
c454t (152 Leu > Phe)
5 26 t125g (42 Val > Gly);
a752t (251 Tyr > Phe);
g1249a (417 Glu > Lys)
19 NCTC8325
SA_520 CC45 1 30 t329c (110 Ile > Thr);
g340t (114 Val > Phe);
t346g (116 Ser > Ala); t349a (117 Leu > Ile);
gta355ttg (119 Val > Leu);
tca361att (121 Ser > Ile);
gt364aa (122 Val > Lys);
c452t (151 Thr > Ile);
c454t (152 Leu > Phe)
5 25 t125g (42 Val > Gly);
a752t (251 Tyr > Phe);
19 NCTC8325
SA_170015 CC45 1 30 t329c (110 Ile > Thr);
g340t (114 Val > Phe);
t346g (116 Ser > Ala); t349a (117 Leu > Ile);
gta355ttg (119 Val > Leu);
tca361att (121 Ser > Ile);
gt364aa (122 Val > Lys);
c452t (151 Thr > Ile);
c454t (152 Leu > Phe)
5 26 t125g (42 Val > Gly);
a752t (251 Tyr > Phe);
t307c (103; I > T)
19 NCTC8325
SA_180015 CC8
ST8
1   a409 (138Lys/del -1 bp) 2 NCTC8325
SA_190006 CC8
ST72
1 24 t125g (42 Val > Gly);
a185c (262 Asp>Ala);
c773t (258 Phe > Ile)
2 NCTC8325
SA_70002 CC8
ST72
1 24 t125g (42 Val > Gly);
a185c (262 Asp>Ala);
c773t (258 Phe > Ile)
2 NCTC8325
SA_103 CC5 2 1 c287t (96; Ser > Leu) N315
SA_80004 CC5 2 1 t313 (138 Phe/del -1 bp) N315
SA_170006 CC5
ST_125
2 1 t361c (121; I > T) N315
SA_180009 CC5
ST_125
2 N315
SA_10009 CC15 2 1 11 5 a407g (136 Lys > Arg) N315
SA_10014 CC15 2 1 11 5 a407g (136 Lys > Arg) N315
SA_80001 CC30 3 13 a145c (49 Ile/Leu);
a343t (115 Ile/Leu)
3 7 g163a (55 Gly > Arg) 12 MW2
SA_107 CC30 3 13 a145c (49 Ile/Leu);
a343t (115 Ile/Leu)
3 7 g163a (55 Gly > Arg) 12 MW2
  1. a Clonal Complex
  2. b Total number of single nucleotide polymorphism including synonymous and non-synonymous mutations