Sub-inhibitory concentrations of oxacillin modify the expression of agr locus in Staphylococcus aureus clinical strains belonging to different clonal complexes

Table 2 Expression levels changes in RNAIII and agrA locus under the exposure to oxacillin subMICs in the stationary growth phase

	RNAIII			agrA
Strain	subMIC OXA^a vs. No subMIC OXA Fold_Change		P ^b;c	subMIC OXA vs. No subMIC OXA Fold_Change		P
SA_123	1.08	NEG	0.735	1.71	POS	0.128
SA_520	1.62	POS	0.028	1.69	POS	0.043
SA_170015	2.11	POS	0.046	1.51	POS	0.116
SA_180015	3.88	POS	0.028	1.65	POS	0.138
SA_190006	1.19	POS	0.465	1.46	POS	0.080
SA_70002	1.12	POS	0.144	1.99	POS	0.144
SA_80004	2.90	POS	0.018	2.55	POS	0.046
SA_103	1.32	POS	0.465	1.13	NEG	0.465
SA_170006	3.69	NEG	0.043	1.12	POS	0.398
SA_180009	20.58	POS	0.068	5.63	POS	0.028
SA_10009	4.23	POS	0.012	8.91	POS	0.028
SA_10014	1.43	POS	0.091	1.65	POS	0.018
SA_80001	1.31	POS	0.249	1.34	NEG	0.028
SA_107	12.08	NEG	0.028	1.37	NEG	0.345

^a OXA: Oxacillin
^b POS: fold change positive in the expression level under exposure to oxacillin subMIC. NEG: fold change negative in the expression level under exposure to oxacillin subMICs
^c Bold numbers indicate statistical significant results (P < 0.05)

ISSN: 1471-2334