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Table 3 Adjusted and unadjusted binary logistic regression analysis showing determinants of non adherence to ART

From: Factors affecting adherence to antiretroviral therapy among pregnant women in the Eastern Cape, South Africa

Variables

Adherence

(n = 1098; 69%)

Non-adherence

(n = 494; 31.0%)

Unadjusted odd ratio

Adjusted odd ratio

Age

  < 25 years

230(63.5)

132(36.5)

1.36(1.06–1.74)*

0.80(0.61–1.04)

  ≥ 25 years

863(70.4)

362(29.6)

Ref

Ref

Marital Status

 Married

230(76.9)

69(23.1)

Ref

Ref

 Single

760(69.5)

333(30.5)

1.40(1.04–1.87)*

1.22(0.89–1.66)

 Co-habiting

95(54.0)

81(46.0)

2.38(1.59–3.56)***

1.71(1.11–2.64)*

 Divorce/Separated

13(54.2)

11(45.8)

2.79 (1.16–6.70)*

3.24(1.33–7.91)*

Educational Level

 No formal education

1(20.0)

4(80.0)

6.97(0.75–64-86)

4.79(0.47–48.91)

 Grade 1–6

85(82.5)

18(17.5)

0.48(0.25–0.90)*

0.51(0.26–0.98)*

 Grade 7–12

947(68.4)

438(31.6)

0.91(0.59–1.39)

0.79(0.50–1.24)

 Tertiary

65(65.7)

34(34.3)

Ref

Ref

Employment Status

 Unemployed

815(68.5)

374(31.5)

0.94(0.73–1.20)

 

 Employed

283(70.2)

120(29.8)

Ref

 

Smoking Habit

 Smoked during pregnancy

33(39.3)

51(60.7)

4.0(2.45–6.53)***

1.91(1.10–3.33)*

 Quit smoking during pregnancy

48(61.5)

30(38.5)

1.51(0.94–2.44)

1.12(0.66–1.88)

 Never smoked

1017(71.1)

413(28.9)

Ref

Ref

Alcohol Use

 Drank during pregnancy

92(44.0)

117(56.0)

3.80(2.76–5.24)***

3.19(2.23–4.56)***

 Stopped duringpregnancy

266(64.9)

144(35.1)

1.55(1.20–1.99)**

1.38(1.05–1.80)*

 Never drank

740(76.1)

233(23.9)

Ref

Ref

HIV status at booking

 Positive

914(70.9)

376(29.1)

Ref

 

 Negative

53(63.9)

30(36.1)

1.08(0.66–1.77)

 

 Unknown

131(59.8)

88(40.2)

1.39 (1.02–1.89)*

 

On ART at booking

 No

263(71.7)

104(28.3)

1.28(0.98–1.67)

 

 Yes

659(70.6)

275(29.4)

Ref

 

Disclosure to partner

 No

256(64.8)

139(35.2)

1.52(1.17–1.97)**

 

 Yes

836(70.3)

353(29.7)

Ref

 

Disclosure to a family member

 No

188(60.8)

121(39.2)

1.30(1.02–1.66)*

1.50(1.13–1.98)*

 Yes

906(70.9)

372(29.1)

Ref

Ref

Trimester at booking

 First

95(57.2)

71(42.8)

1.22(0.69–2.16)

1.34(0.74–2.42)

 Second

843(71.6)

335(28.4)

0.73(0.55–0.97)*

0.79(0.58–1.06)

 Third

160(64.5)

88(35.5)

Ref

Ref

  1. Ref: Reference; Model adjusted for disclosure to sexual partner, HIV status at booking, on ART at booking and employment status, *** represents p-value <0.000, ** represents p-value less than 0.01, * represent p-value < 0.05
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BMC Infectious Diseases

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