Table 1 Baseline and demographic characteristics of individuals (n = 4003) older and younger with HIV infection on antiretroviral treatment (ART) from June 2004 to December 2012
Characteristics | Older (≥ 50 years) N = 262 | Younger (< 50 years) N = 3741 | p-value |
|---|---|---|---|
Year of entry | – | ||
2004 | 2 (0.8) | 74 (2.0) | |
2005 | 34 (13.0) | 568 (15.2) | |
2006 | 39 (14.9) | 574 (15.3) | |
2007 | 18 (6.9) | 270 (7.2) | |
2008 | 11 (4.2) | 181 (4.8) | |
2009 | 34 (13.0) | 369 (9.9) | |
2010 | 60 (22.9) | 877 (23.4) | |
2011 | 54 (20.6) | 655 (17.5) | |
2012 | 10 (3.8) | 173 (4.6) | |
Age (years), median (IQR) | 54. 5 (52–58) | 32 (28–38) | – |
Gender, n (%) | |||
Male | 117 (44.7) | 1321 (35.3) | 0.003 |
Female | 145 (55.3) | 2420 (64.7) | |
Clinic site, n (%) | 0.021 | ||
Urban | 99 (37.8) | 1691 (45.2) | |
Rural | 163 (62.2) | 2050 (54.8) | |
Median body mass index (kg/m2), (IQR)a | 23.1 (20.5–27.1) | 22.8 (20.2–26.4) | 0.154 |
Baseline CD4+ count, (cells/μl) median(IQR)b | 142 (86–197) | 124 (60–184) | < 0.001 |
CD4+ cell count, cells/mm3: n (%) | 0.119 | ||
< 200 | 173 (76.5) | 2747 (81.2) | |
200–350 | 45 (19.9) | 568 (16.8) | |
> 350 | 8 (3.5) | 70 (2.1) | |
Viral load (log copies/ml), mean (SD)e | 4.9 (1.0) | 5.0 (0.9) | 0.268 |
WHO stage, n (%)c | 0.623 | ||
1 | 40 (15.3) | 556 (14.9) | |
2 | 60 (22.9) | 744 (20.0) | |
3 | 131 (50.0) | 2004 (53.8) | |
4 | 31 (11.8) | 424 (11.4) | |
Past history of TB, n (%)d | 62 (24.2) | 1077 (29.5) | 0.075 |
Prevalent TB, n (%) | 62 (23.7) | 907 (24.2) | 0.882 |
Co-morbidities | |||
Hypertensione | 55 (21.5) | 79 (2.2) | <.001 |
Diabetesf | 16 (6.3) | 24 (0.7) | <.001 |
Occupationg | 0.014 | ||
Employed | 83 (32.2) | 1193 (32.3) | |
Unemployed | 156 (60.5) | 2358 (63.9) | |
Scholar/Other | 19 (7.4) | 137 (3.7) | |
Initial ART regimen | |||
2NRTI + NNRTI | 260 (100%) | 3718 (99.6%) | |
2NRTI + PI | 0 | 15 (0.4%) | |