Pre-intervention period | Intervention period | P value | |
---|---|---|---|
No. of prescriptions | 303 | 272 | |
Male, n (%) | 181 (59.7) | 163 (59.9) | 0.963 |
Age, median years (IQR) | 60 (48–71) | 61 (49–72) | 0.528 |
Comorbid condition, n (%) | |||
Diabetes mellitus | 68 (22.4) | 53 (19.5) | 0.385 |
Chronic liver disease | 28 (9.2) | 27 (9.9) | 0.780 |
Chronic lung disease | 10 (3.3) | 1 (0.4) | 0.010 |
Cerebrovascular disease | 10 (3.3) | 11 (4.0) | 0.635 |
Solid malignancy | 86 (28.4) | 68 (25.0) | 0.360 |
Hematological malignancy | 58 (19.1) | 72 (26.5) | 0.036 |
Connective tissue disease | 8 (2.6) | 8 (2.9) | 0.827 |
Azotemia | 46 (15.2) | 46 (16.9) | 0.572 |
Neutropenia | 61 (20.1) | 63 (23.2) | 0.378 |
Suspected site of infection, n (%) | 0.214 | ||
Pneumonia | 68 (22.4) | 50 (18.4) | |
Intraabdominal infection | 32 (10.6) | 42 (15.4) | |
CNS infection | 34 (11.2) | 32 (11.8) | |
Skin and soft tissue infection | 62 (20.5) | 50 (18.4) | |
Cardiovascular infection | 2 (0.7) | 5 (1.8) | |
Catheter-related infection | 25 (8.3) | 16 (5.9) | |
Bone and joint infection | 31 (10.2) | 8 (2.9) | |
Urinary tract infection | 5 (1.7) | 3 (1.1) | |
Other infection | 19 (6.3) | 19 (7.0) | |
Unknown | 25 (8.3) | 47 (17.3) | |
Admission department, n (%) | 0.303 | ||
Medial ward | 165 (54.5) | 176 (64.7) | |
Surgical ward | 86 (28.4) | 46 (16.9) | |
Medical ICU | 33 (10.9) | 30 (11.0) | |
Surgical ICU | 19 (6.3) | 20 (7.4) | |
30-days mortality, n (%) | 53 (17.5) | 37 (13.6) | 0.200 |