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Table 3 Univariate Cox regression analysis: variables associated with death in 65 HIV/HCV-coinfected patients with decompensated cirrhosis

From: Prognostic value of liver stiffness in HIV/HCV-Coinfected patients with decompensated cirrhosis

Variable Univariate Analysis
HR 95% CI P
Sex (male vs female) 0.887 0.417–1.887 .755
Age (per year) 1.011 0.943–1.085 .749
Year of decompensation (≤2008 vs > 2008) 1.238 0.563–2.724 .596
Alcohol intake > 50 g/day (yes vs no) 1.232 0.522–2.905 .634
HBsAg (positive vs negative) 1.210 0.366–4.005 .754
Nadir CD4+ (per cell/mm3) 1.000 0.997–1.003 .920
Baseline CD4+ (per cell/mm3) 0.999 0.997–1.001 .489
Esophageal varices (yes vs no) 0.729 0.336–1.582 .424
Liver stiffness (per kPa) 1.017 0.998–1.037 .078
Serum albumin (per g/dL) 0.482 0.298–0.780 .003
FIB-4 (per unit) 1.095 1.024–1.171 .008
Child-Pugh score (per unit) 1.356 1.100–1.671 .004
MELD score (per unit) 1.111 1.022–1.209 .014
LSPS (per unit) 1.023 0.987–1.060 .220
Anti-HCV therapya (no vs yes) 1.340 0.300–5.920 .695
  1. Abbreviations: HIV human immunodeficiency virus, HCV hepatitis C virus, HR hazard ratio, CI confidence interval, HBsAg hepatitis B surface antigen, MELD model for end-stage liver disease, LSPS liver stiffness × spleen diameter/platelet ratio
  2. aComputed as a time-dependent variable