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Table 3 Univariate Cox regression analysis: variables associated with death in 65 HIV/HCV-coinfected patients with decompensated cirrhosis

From: Prognostic value of liver stiffness in HIV/HCV-Coinfected patients with decompensated cirrhosis

Variable

Univariate Analysis

HR

95% CI

P

Sex (male vs female)

0.887

0.417–1.887

.755

Age (per year)

1.011

0.943–1.085

.749

Year of decompensation (≤2008 vs > 2008)

1.238

0.563–2.724

.596

Alcohol intake > 50 g/day (yes vs no)

1.232

0.522–2.905

.634

HBsAg (positive vs negative)

1.210

0.366–4.005

.754

Nadir CD4+ (per cell/mm3)

1.000

0.997–1.003

.920

Baseline CD4+ (per cell/mm3)

0.999

0.997–1.001

.489

Esophageal varices (yes vs no)

0.729

0.336–1.582

.424

Liver stiffness (per kPa)

1.017

0.998–1.037

.078

Serum albumin (per g/dL)

0.482

0.298–0.780

.003

FIB-4 (per unit)

1.095

1.024–1.171

.008

Child-Pugh score (per unit)

1.356

1.100–1.671

.004

MELD score (per unit)

1.111

1.022–1.209

.014

LSPS (per unit)

1.023

0.987–1.060

.220

Anti-HCV therapya (no vs yes)

1.340

0.300–5.920

.695

  1. Abbreviations: HIV human immunodeficiency virus, HCV hepatitis C virus, HR hazard ratio, CI confidence interval, HBsAg hepatitis B surface antigen, MELD model for end-stage liver disease, LSPS liver stiffness × spleen diameter/platelet ratio
  2. aComputed as a time-dependent variable