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Table 4 MMSE and changes of CSF measures and serum RPR titer in CSF RPR- patients by follow-up

From: The performance of rapid plasma reagin (RPR) titer in HIV-negative general paresis after neurosyphilis therapy

Variable

pre-treatment

12 months after treatment

P

Increased CSF WBC count

2/6(33%)

1/6(17%)

0.505

Increased CSF protein concentration

6/6(100%)

1/6(17%)

0.003

Four-fold decline in CSF RPR

Four-fold decline in serum RPR

3/6(50%)

Median MMSE (IQR)

14.5(11–18.25)

17(13–19.25)

0.048

  1. Increased CSF WBC count means CSF WBC count > 5 cells/μl; Increased CSF protein concentration means CSF protein concentration > 45 mg/dl; RPR, rapid plasma regain; MMSE, mini-mental state examination