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Table 3 MMSE and changes of CSF measures and serum RPR titer in CSF RPR+ patients by follow-up

From: The performance of rapid plasma reagin (RPR) titer in HIV-negative general paresis after neurosyphilis therapy

Variable

pre-treatment

12 months after treatment

P

Increased CSF WBC counta

5/12(42%)

0/12(0%)

0.012

Increased CSF protein concentrationa

7/12(58%)

2/12(17%)

0.035

Four-fold decline in CSF RPR

11/13(85%)

Four-fold decline in serum RPR

6/13(46%)

Median MMSE (IQR)

13(9.5–15)

19(16.5–20.5)

< 0.001

  1. Increased CSF WBC count means CSF WBC count > 5 cells/μl; Increased CSF protein concentration means CSF protein concentration > 45 mg/dl; RPR, rapid plasma regain; MMSE, mini-mental state examination; aData are for 12 patients