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Table 1 Sociodemographic and clinical characteristics of invasive pneumococcal disease (IPD) case-patients and community controls

From: Effectiveness of 13-pneumococcal conjugate vaccine (PCV13) against invasive pneumococcal disease in children in the Dominican Republic

Factor

Case-patient (%)

N = 39

Control (%)

N = 149

Matched p-value

Age < 6 months

12 (31)

47 (32)

1.00

Female sex

17 (44)

74 (50)

0.54

Born in the Dominican Republic

38 (97)

145 (97)

1.00

Lives in urban area

26 (67)

102 (68)

1.00

Family owns a home

7 (18)

75 (50)

0.0002

Living conditions

 Home with dirt floora

2 (5)

4 (3)

0.73

 Home built of wooda

12 (31)

19 (13)

0.01

 Has electricity

1 (3)

3 (2)

1.00

 Has indoor bathroom

23 (59)

107 (72)

0.14

Means of cooking

 Coal

1 (3)

21 (14)

0.06

 Gas

36 (92)

139 (93)

1.00

 Firewood

3 (8)

16 (11)

0.69

Cooking done in room where others congregate or sleep

12 (31)

23 (15)

0.08

Lives with ≥1 child < 5 years

17 (44)

42 (28)

0.09

Crowding index (> 2 persons/room)

14 (36)

88 (59)

0.01

Breastfed in the last month

18 (46)

50 (34)

0.12

History of ≥1 household member smoking inside in the last month

4 (10)

21 (14)

0.76

Mother completed primary school

26 (67)

115 (77)

0.22

Low birthweight (< 2500 g)

3 (8)

14 (9)

1.00

Born premature (< 36 weeks)

1 (3)

8 (5)

0.88

Low weight-for-age Z score (<−2 SD)

11 (28)

13 (9)

0.003

History of comorbidities

7 (18)

33 (22)

0.71

History of another infection in last 12 months

15 (38)

47 (32)

0.20

History of medical consultation for respiratory infection in last 12 months

32 (82)

133 (89)

0.46

History of cold or cough in the last month

21 (54)

124 (83)

0.001

Up-to-date with PCVb

11 (28)

66 (44)

0.02

Number of valid PCV doses

 0

15 (38)

30 (20)

 1

6 (15)

44 (30)

0.01

 2

18 (46)

59 (40)

0.25

 3

0 (0)

16 (11)

0.002

  1. aHomes with dirt floors and built of wood are considered lower quality materials (i.e. low socioeconomic proxy) compared to reference categories of higher quality material, i.e. cement, brick
  2. bOne valid PCV dose for children aged ≤4 months and 13 days, at least two valid doses for children aged between 4 months plus 14 days and ≤ 12 months plus 13 days, and at least three valid doses for children ≥12 months plus 14 days at the time of hospital admission or reference day