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Table 2 Frequency of G6PD deficiency and G6PD variants in Myanmar malaria patients

From: Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among malaria patients in Upper Myanmar

  Amino acid substitution WHO classificationa Female Male Total (%)
Normal    30 172 202 (80.1)
G6PD deficiency    7 43 50 (19.9)
Vanua Lava (383T>C) L128P II 0 0 0 (0.0)
Mahidol
(487G>A)
G163S III 3 31 34 (13.5)
Mediterranean (563C>T) S188F II 1 1 2 (0.8)
Coimbra
(592C>T)
R198C II 0 0 0 (0.0)
Viangchan
(871G>A)
V291M III 0 3 3 (1.2)
Union
(1360C>T)
R454C II 0 1 1 (0.4)
Canton
(1376G>T)
R459L III 1 0 1 (0.4)
Kaiping
(1388G>A)
R463H II 2 7 9 (3.6)
  1. aClass I, severe deficiency (<10% activity) with chronic (nonspherocytic) hemolytic anemia; class II, severe deficiency (<10% activity) with intermittent hemolysis severe deficiency; class III, mild deficiency (10-60% activity) hemolysis with stressors only; class IV, non-deficient, variant, no clinical sequelae (50-150% activity); Class V: Increased enzyme activity, no clinical sequelae (150>% activity)