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Table 1 Distribution of human plague cases and deaths from January 1, 2000 to December 31, 2012 in Qing Hai province, China

From: Continuous hypoxia reduces the concentration of streptomycin in the blood

Case From the region Initial case (Y/N)a Die or not (Y/N) Normal dose (Y/N)
1 Nangqian Y Y(died in 3 days) N (no streptomycin)
2 Nangqian Y Y(died in 3 days) N (no streptomycin)
3 Nangqian N Y(died in 3 days) N (no streptomycin)
4 Nangqian N Y(died in 3 days) N (no streptomycin)
5 Nangqian N Y(died in 3 days) N (no streptomycin)
6 Nangqian N Y(died in 3 days) N (no streptomycin)
7 Nangqian N N N
8 Nangqian N N N
9 Nangqian N N N
10 Nangqian N N N
11 Nangqian N N N
12 Nangqian N N N
13 Nangqian N N N
14 Nangqian N N N
15 Xinghai N Y(died in 5 days) Y
16 Xinghai N Y(died in 5 days) Y
17 Xinghai Y Y(died in 3 days) N (no streptomycin)
18 Xinghai N N N
19 Xinghai N N N
20 Xinghai N N N
21 Xinghai N N N
22 Xinghai N N N
23 Xinghai N N N
24 Xinghai N N N
25 Xinghai N N N
26 Xinghai N N N
27 Langxian N N N
28 Langxian N N N
29 Langxian N N N
30 Langxian N N N
31 Langxian N N N
32 laboratory staff N N N
  1. aInitial case: “Y” means plague symptoms due to direct contact with marmots; “N” means plague symptoms due to closely contact with plague patients
  2. The cause of death in Nangqian was mainly related to the delay of diagnosis. After that, with the increased level of diagnosis in plague, the mortality rate decreased significantly. Only one patient died quickly in Xinghai, and patients with a history of close contact were quickly isolated and treated well, except for 2 patients who were treated with conventional dose of streptomycin