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Table 3 Factors related to sputum culture conversion amongst multidrug-resistant patients in Jiangsu Province, China (N = 139)

From: Factors affecting time to sputum culture conversion and treatment outcome of patients with multidrug-resistant tuberculosis in China

Variable N (%) HR 95% CI P-value
Age, years
  ≤ 51 99 (71.4) Reference   
  > 51 40 (28.6) 0.77 0.53–1.14 0.190
Gender
 Male 71 (51.1) Reference   
 Female 68 (48.9) 0.90 0.59–1.36 0.604
Weight, kilograms
  ≤ 60 79 (56.8) Reference   
  > 60 60 (43.2) 0.91 0.62–1.33 0.607
Smoking
 No 72 (51.8) Reference   
 Yes 65 (46.8) 0.63 0.43–0.93 0.020
 Missing 2 (1.4)    
Drinking
 No 86 (61.9) Reference   
 Yes 26 (18.7) 0.49 0.27–0.89 0.019
 Missing 27 (19.4)    
Ofloxacin
 Drug sensitive 103 (74.1) Reference   
 Drug resistance 15 (10.8) 0.46 0.29–0.73 0.001
 Missing 21 (15.1)    
Kanamycin
 Drug sensitive 81 (30.2) Reference   
 Drug resistance 42 (58.3) 0.72 0.37–1.38 0.320
 Missing 16 (11.5)    
Sputum smear grade
  ≤ 1 51 (36.7) Reference   
  > 1 87 (62.6) 0.61 0.41–0.91 0.001
 Missing 1 (0.7)    
Lung lesions
 No 3 (2.2) Reference   
 Yes 129 (92.8) 1.17 0.79–1.71 0.436
 Missing 7 (5.0)    
Baseline regimens
 SR 77 (55.4) Reference   
 IR 62 (44.6) 1.34 0.76–2.37 0.32
  1. Abbreviations: HR hazard ratio, CI confidence interval, IR individualized regimens, SR standard regimen. SR: include SR1, SR2, SR3 and SR4 regiments