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Table 3 Factors related to sputum culture conversion amongst multidrug-resistant patients in Jiangsu Province, China (N = 139)

From: Factors affecting time to sputum culture conversion and treatment outcome of patients with multidrug-resistant tuberculosis in China

Variable

N (%)

HR

95% CI

P-value

Age, years

  ≤ 51

99 (71.4)

Reference

  

  > 51

40 (28.6)

0.77

0.53–1.14

0.190

Gender

 Male

71 (51.1)

Reference

  

 Female

68 (48.9)

0.90

0.59–1.36

0.604

Weight, kilograms

  ≤ 60

79 (56.8)

Reference

  

  > 60

60 (43.2)

0.91

0.62–1.33

0.607

Smoking

 No

72 (51.8)

Reference

  

 Yes

65 (46.8)

0.63

0.43–0.93

0.020

 Missing

2 (1.4)

   

Drinking

 No

86 (61.9)

Reference

  

 Yes

26 (18.7)

0.49

0.27–0.89

0.019

 Missing

27 (19.4)

   

Ofloxacin

 Drug sensitive

103 (74.1)

Reference

  

 Drug resistance

15 (10.8)

0.46

0.29–0.73

0.001

 Missing

21 (15.1)

   

Kanamycin

 Drug sensitive

81 (30.2)

Reference

  

 Drug resistance

42 (58.3)

0.72

0.37–1.38

0.320

 Missing

16 (11.5)

   

Sputum smear grade

  ≤ 1

51 (36.7)

Reference

  

  > 1

87 (62.6)

0.61

0.41–0.91

0.001

 Missing

1 (0.7)

   

Lung lesions

 No

3 (2.2)

Reference

  

 Yes

129 (92.8)

1.17

0.79–1.71

0.436

 Missing

7 (5.0)

   

Baseline regimens

 SR

77 (55.4)

Reference

  

 IR

62 (44.6)

1.34

0.76–2.37

0.32

  1. Abbreviations: HR hazard ratio, CI confidence interval, IR individualized regimens, SR standard regimen. SR: include SR1, SR2, SR3 and SR4 regiments