Table 4 Factors associated with unsuccessful treatment outcomes among new pulmonary smear-positive tuberculosis patients registered during 2005–2013 in Anqing, China (n = 14,842)
Variables | Total (n = 14,842) | Unsuccessful (n = 739) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | ||||
Sex | Female | 3793 (25.56) | 177 (4.67) | 1 | |||
Male | 11,049 (74.44) | 562 (5.09) | 1.09 (0.92, 1.30) | 0.30 | |||
Age | 15~ 24 | 1960 (13.21) | 48 (2.45) | 1 | 1 | ||
25~ 34 | 1567 (10.56) | 49 (3.13) | 1.29 (0.86, 1.93) | 0.22 | 1.31 (0.81, 2.11) | 0.28 | |
35~ 44 | 2412 (16.25) | 87 (3.61) | 1.49 (1.04, 2.13) | 0.03 | 1.56 (1.00, 2.42) | 0.049 | |
45~ 54 | 2340 (15.77) | 113 (4.83) | 2.02 (1.43, 2.85) | < 0.001 | 2.12 (1.38, 3.60) | < 0.001 | |
55~ 64 | 3269 (22.03) | 182 (5.57) | 2.35 (1.70, 3.24) | < 0.001 | 2.32 (1.52, 3.53) | < 0.001 | |
≥65 | 3294 (22.19) | 260 (7.89) | 3.41 (2.50, 4.67) | < 0.001 | 3.08 (2.03, 4.68) | < 0.001 | |
Ethnicity | Han | 14,819(99.85) | 739 (4.99) | – | 0.63 | ||
Other | 23 (0.15) | 0 | 1 | ||||
Occupation | Student | 807 (5.44) | 21 (2.60) | 1 | |||
Official staff | 190 (1.28) | 6 (3.16) | 1.22 (0.49, 3.07) | 0.67 | |||
Service | 277 (1.87) | 9 (3.25) | 1.26 (0.57, 2.78) | 0.57 | |||
Worker | 1214 (8.18) | 54 (4.45) | 1.74 (1.04, 2.91) | 0.03 | |||
Farmer | 11,567 (77.93) | 618 (5.34) | 2.11 (1.36, 3.28) | < 0.001 | |||
Retired staff | 261 (1.76) | 16 (6.13) | 2.44 (1.26, 4.76) | 0.009 | |||
Unemployment | 198 (1.33) | 7 (3.54) | 1.37 (0.58, 3.27) | 0.48 | |||
Other | 328 (2.21) | 8 (2.44) | 0.94 (0.41, 2.13) | 0.87 | |||
Way of discovering patients | Health examination | 112 (0.75) | 4 (3.57) | 1 | |||
Contact examination | 12 (0.08) | 1 (8.33) | 2.46 (0.25, 23.94) | 0.44 | |||
Clinic visit due to symptoms | 6716 (45.25) | 294 (4.38) | 1.24 (0.45, 3.38) | 0.68 | |||
Recommended due to symptoms | 204 (1.37) | 17 (8.33) | 2.46 (0.81, 7.48) | 0.11 | |||
Referral | 7137 (48.09) | 370 (5.18) | 1.48 (0.54, 4.03) | 0.45 | |||
Tracing | 637 (4.29) | 52 (8.16) | 2.40 (0.85, 6.77) | 0.10 | |||
Other | 24 (0.16) | 1 (4.17) | 1.17 (0.13, 11.00) | 0.89 | |||
Treatment management models | Self-medication | 8 (0.05) | 6 (75.00)3 | 67.72(13.65, 336.07) | < 0.001 | 70.38 (12.97, 381.85) | < 0.001 |
Full-course supervision | 14,512 (97.78) | 615 (4.24) | 1 | 1 | |||
Full-course management | 122 (0.82) | 50 (40.98) | 15.69(10.84, 22.71) | < 0.001 | 16.45 (11.17, 24.22) | < 0.001 | |
Supervision in intensive phase | 200 (1.35) | 68 (34.00) | 11.64(8.59, 15.77) | < 0.001 | 10.86 (7.91, 14.91) | < 0.001 | |
X-Ray | Normal | 286 (1.93) | 1 (0.35) | 0.07(0.01, 0.47) | 0.007 | 0.09 (0.01, 0.63) | 0.016 |
Abnormal | 14,447 (97.34) | 726 (5.03) | 1 | 1 | |||
Unchecked | 109 (0.73) | 12 (11.01) | 2.34(1.28, 4.28) | 0.006 | 2. 70 (1.41, 5.16) | 0.003 | |
Cavity | Yes | 2527 (17.03) | 154 (6.09) | 1.30 (1.08, 1.56) | 0.005 | 1.42 (1.18, 1.73) | < 0.001 |
No | 12,315 (82.97) | 585 (4.75) | 1 | 1 | |||
Miliary | Yes | 99 (0.67) | 14 (14.14) | 3.18 (1.80, 5.63) | < 0.001 | 3.39 (1.87, 6.13) | < 0.001 |
No | 14,743 (99.33) | 725 (4.92) | 1 | 1 | |||
Regimen | Regimen 1a | 12,470 (84.02) | 610 (4.89) | 1 | |||
Regimen 2b | 2372 (15.98) | 129 (5.44) | 1.12 (0.92, 1.36) | 0.26 | |||
Total delay | ≤17 | 3965 (26.71) | 181 (4.56) | 1 | |||
17~ 33 | 3632 (24.47) | 173 (4.76) | 1.05 (0.85, 1.29) | 0.68 | |||
33~ 66 | 3594 (24.22) | 164 (4.56) | 1.00 (0.81, 1.24) | > 0.99 | |||
> 66 | 3651 (24.60) | 221 (6.05) | 1.35 (1.10, 1.65) | 0.004 | |||